Hostname: page-component-78c5997874-4rdpn Total loading time: 0 Render date: 2024-11-20T02:28:02.150Z Has data issue: false hasContentIssue false

Calcium Metabolism in States of Depression

Published online by Cambridge University Press:  29 January 2018

Frederic F. Flach*
Affiliation:
Payne Whitney Clinic, 525 East 68th Street, New York, 21, New York

Extract

We have previously demonstrated, in small groups of patients receiving either electric convulsive treatments or imipramine therapy, changes in calcium metabolism associated with recovery from states of depression (5, 7). Other investigators have also reported somewhat unusual changes in calcium physiology among depressed patients or during the administration of antidepressant therapies. These include low cerebrospinal fluid calcium levels (4), changes in blood calcium during electric convulsive treatments (10), and alterations in bound and ionized fractions of blood calcium during imipramine therapy (3). It is the purpose of this report to describe and discuss the changes in urinary calcium excretion in the relatively large series of patients we have now acquired.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1964 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1 Anderson, W. McC., and Dawson, J. (1962). “The clinical manifestations of depressive illness with abnormal acetyl methyl carbinol metabolism.” J. Ment. Sci., 108, 452.CrossRefGoogle Scholar
2 Boszormenyi-Nagy, I., and Gerty, Francis J. (1955). “Diagnostic aspects of a study of intracellular phosphorylations in schizophrenia.” Amer, J. Psychiat., 112, 11.CrossRefGoogle Scholar
3 Coirault, R., et al. (1959). “Les variations du calcium sanguin total, du calcium sanguin ionisé et du calcium urinaire/24 heures au cours de la sismotherapie et des traitements chimiothérapiques à action anxiolytique.” (Imipramine et Nialamid.) Medicina Experimentalis, 1, 1.Google Scholar
4 Eiduson, S., Brill, N., and Crumpton, E. (1960). “The effect of electro-convulsive therapy on spinal fluid constituents.” J. Ment. Sci., 106, 692.CrossRefGoogle Scholar
5 Flach, Frederic F., et al. (1960). “The effects of electric convulsive treatments on nitrogen, calcium and phosphorus metabolism in psychiatric patients.” Ibid., 106, 443.Google Scholar
6 Flach, Frederic F., et al. (1961). “A study of the reliability of the social behavior chart.” Comp. Psychiat., 2, 2.CrossRefGoogle Scholar
7 Flach, Frederic F., et al. (1961). “Alterations in calcium metabolism in depressed patients receiving imipramine.” Proceedings of the Third World Congress of Psychiatry. Montreal, Canada.Google Scholar
8 Flach, Frederic F., et al. (1962). “Factors influencing the reliability of the social behavior chart.” Comp. Psychiat., 3, 5.CrossRefGoogle Scholar
9 Flach, Frederic F., et al. and Liang, Edward (1963). “The operation of a metabolic unit in psychiatry.” J. Nerv. Ment. Dis., 137, 1.CrossRefGoogle Scholar
10 Gour, K., and Chaudhry, H. (1957). “Study of calcium metabolism in electroconvulsive therapy (E.C.T.) in certain mental diseases.” J. Ment. Sci., 103, 275.CrossRefGoogle Scholar
11 Wheaton, G. D., et al. (1949). “Modification of the effect of immobilization upon metabolic and physiologic functions of normal men by the use of the oscillating bed.” Amer. J. Med., 6, 684.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.