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A Beta Adrenergic Stimulant (Salbutamol) versus Clomipramine in Depression: A Controlled Study

Published online by Cambridge University Press:  29 January 2018

Y. Lecrubier ,
A. J. Puech ,
R. Jouvent ,
P. Simon  and
D. Widlocher
Y. Lecrubier
Affiliation:
Département de Psychiatrie Adulte, Hôpital de la Salpêtrière, 47 Boulevard de l'Hôpital, 75013 Paris, France
A. J. Puech
Affiliation:
Departement de Pharmacologie Clinique, Hôpital de la Pitié Salpêtrière, 91 Boulevard de l'Hôpital, 75013, Paris, France
R. Jouvent
Affiliation:
Département de Psychiatrie Adulte, Hôpital de la Salpêtrière, 47 Boulevard de l'Hôpital, 75013 Paris, France
P. Simon
Affiliation:
Departement de Pharmacologie Clinique, Hôpital de la Pitié Salpêtrière, 91 Boulevard de l'Hôpital, 75013, Paris, France
D. Widlocher
Affiliation:
Département de Psychiatrie Adulte, Hôpital de la Salpêtrière, 47 Boulevard de l'Hôpital, 75013 Paris, France
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Summary

A controlled study comparing salbutamol (6 mg/day) to clomipramine (150 mg/day), both given by intravenous infusion, was performed on depressed inpatients (10 per group). The symptomatology was evaluated by two blind observers at days 0, 5 and 15 using the Hamilton Rating Scale. Both treatments were effective on the overall symptomatology but the onset of action of salbutamol was more rapid.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 136 , Issue 4 , April 1980 , pp. 354 - 358
Copyright
Copyright © Royal College of Psychiatrists, 1980 

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References

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