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An American Validation Study of the Newcastle Diagnostic Scale: I. Relationship with the Dexamethasone Suppression Test

Published online by Cambridge University Press:  29 January 2018

M. Zimmerman*
Affiliation:
University of Iowa Hospitals and Clinics, Department of Psychiatry, 500 Newton Road, Iowa City, Iowa 52242, USA
B. Pfohl
Affiliation:
University of Iowa Hospitals and Clinics, Department of Psychiatry, 500 Newton Road, Iowa City, Iowa 52242, USA
D. Stangl
Affiliation:
University of Iowa Hospitals and Clinics, Department of Psychiatry, 500 Newton Road, Iowa City, Iowa 52242, USA
W. Coryell
Affiliation:
University of Iowa Hospitals and Clinics, Department of Psychiatry, 500 Newton Road, Iowa City, Iowa 52242, USA
*
Correspondence

Extract

The Newcastle diagnostic index was completed on 159 depressedin-patients, who received the dexamethasone suppression test during their first week in hospital. Patients suffering from endogenous depression had a significantly higher rate of DST non-suppression, were older, were more frequently psychotic, and more frequently lost weight; even after con trolling for these variables, DST non-suppression was significantly more frequent in the endogenous group. The relationship between Newcastle scores and the frequency of DST non-suppression was non-linear.

Type
Papers
Copyright
Copyright © 1986 The Royal College of Psychiatrists 

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