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Alterations in Cerebral Laterality during Acute Psychotic Illness

Published online by Cambridge University Press:  29 January 2018

Bruce E. Wexler*
Affiliation:
Yale University School of Medicine, and ∗ VA Medical Center, 116/1 West Haven, Connecticut 06516, USA

Abstract

A new dichotic listening test (fused rhymed words) was used to monitor changes in perceptual asymmetry (PA) in patients recovering from acute psychotic episodes; some were also given a dichotic nonsense syllables test, a dichotic tone test, and a single visual field dot localisation test. Contrary to expectation, PA on the word test decreased with recovery, while asymmetry on the tone and dot tests did not change; results cut across diagnosis, could not be related to medication, and were independent of changes in overall performance. More specific hypotheses are needed than those of generalised single hemisphere dysfunction in major psychiatric illness, but existing models and concepts are inadequate to explain the findings.

Type
Papers
Copyright
Copyright © 1986 The Royal College of Psychiatrists 

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References

Colburn, C. H. & Lishman, W. A. (1979) Lateralisation of function and psychotic illness: A left hemisphere deficit? In Hemisphere Asymmetries of Function in Psychopathology (eds. Gruzelier, J. & Flor-Henry, P.). Amsterdam: Elsevier North-Holland Biomedical Press.Google Scholar
Flor-Henry, P. (1979) On certain aspects of the localization of the cerebral systems regulating and determining emotion. Biological Psychiatry, 14, 677698.Google Scholar
Gruzelier, J. H. (1981) Cerbral laterality and psychopathology: Fact and fiction. Psychological Medicine, 11, 219227.Google Scholar
Halwes, T. G. (1969) Effects of dichotic fusion on the perception of speech. Speech Research, New Haven, Connecticut: Haskins Laboratories.Google Scholar
Henninger, G. R., French, W. & Slavinsky, A. T. (1970) A short clinical rating scale for use by nursing personnel. Archives of General Psychiatry, 23, 241248.Google Scholar
Kinsbourne, M. (1975) The interaction between cognitive process and the direction of attention In Attention and Performance (eds. Rabbitt, P. N. A. & Domic, S.) London: Academic Press.Google Scholar
Levy, J. & Reid, M. (1978) Variations in cerebral organization as a function of handedness, hand posture in writing, and sex. Journal of Experimental Psychology, 107, (2) 119144.Google Scholar
Lishman, W. A., Toone, B. K. & Colburn, C. H. (1978) Dichotic listening in psychotic patients. British Journal of Psychiatry, 132, 333341.Google Scholar
Merrin, E. L. (1981) Schizophrenia and brain asymmetry. An evaluation of evidence for dominant lobe dysfunction. The Journal of Nervous and Mental Disease, 169, 405416.Google Scholar
Merrin, E. L. (1982) Clinical characterization of schizophrenic patients and cerebral asymmetry: Review and hypothesis. Comprehensive Psychiatry, 23, 5567.CrossRefGoogle ScholarPubMed
Newlin, D. B., Carpenter, B. & Golden, C. J. (1981) Hemispheric asymmetries in schizophrenia. Biological Psychiatry, 16, 561582.Google Scholar
Riederer, J. (1981) Lateralite cerebrale et troubles psychiques. Revue Medicale de la Suisse Romande, 101(7), 555563.Google Scholar
Spitzer, R., Endicott, J. & Robbins, E. (1975) Research Diagnostic Criteria. New York, New York State Department of Mental Hygiene, New York State Psychiatrie Institute.Google Scholar
Wexler, B. E. (1980) Cerebral laterality and psychiatry: A review of the literature. American Journal of Psychiatry, 137, 279291.Google Scholar
Wexler, B. E. (1986) A model of brain function: Its implications for psychiatric research. British Journal of Psychiatry, 148, 357362.Google Scholar
Wexler, B. E. (1979) Alterations in cerebral laterality in acute psychotic illness. Archives of General Psychiatry, 36, 278284.CrossRefGoogle ScholarPubMed
Wexler, B. E. & Halwes, T. (1981) Right ear bias in the perception of loudness of pure tones. Neuropsychologia, 19, 147–140.Google Scholar
Wexler, B. E. & Halwes, T. (1983) Increasing the power of dichotic methods: The fused rhymed words test Neuropsychologia, 21, 5966.CrossRefGoogle ScholarPubMed
Wexler, B. E. & Halwes, T. (1985) Dichotic listening tests in studying brain-behaviour relationships. Neuropsychologia, 23, 545559.Google Scholar
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