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Age at onset of first episode and time to treatment in in-patients with bipolar disorder

Published online by Cambridge University Press:  02 January 2018

Gunnar Morken ,
Arne E. Vaaler ,
Gunn E. Folden ,
Ole A. Andreassen  and
Ulrik F. Malt
Gunnar Morken*
Affiliation:
⊘stmarka Psychiatric Department, St Olavs Hospital and Institute of Neuroscience, Norwegian University of Technology and Science, Trondheim
Arne E. Vaaler
Affiliation:
⊘stmarka Psychiatric Department, St Olavs Hospital and Institute of Neuroscience, Norwegian University of Technology and Science, Trondheim
Gunn E. Folden
Affiliation:
⊘stmarka Psychiatric Department, St Olavs Hospital and Institute of Neuroscience, Norwegian University of Technology and Science, Trondheim
Ole A. Andreassen
Affiliation:
Department of Psychiatry, Ulleval University Hospital and Institute of Psychiatry, University of Oslo
Ulrik F. Malt
Affiliation:
Department of Neuropsychiatry and Psychosomatic Medicine, Division of Clinical Neurosciences, Rikshospitalet University Hospital and Institute of Psychiatry, University of Oslo, Norway
*
Gunnar Morken, ⊘stmarka Psychiatric Department, St Olavs Hospital, Box 3008 Lade, 7441 Trondheim, Norway. Email: [email protected]
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Abstract

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Summary

This study aimed to investigate the relationship between age at onset and time to first pharmacological treatment in patients with either bipolar I or II disorder. A total of 146 consecutive in-patients acutely admitted from the same catchment area were included. Patients were divided into four age groups: 0–12 years (23%); 13–18 years (32%); 19–29 years (26%); and 30 years (18%). Mean age at first affective episode was 20.2 years (s.d.=11.8). This represents a similar pattern to the age at onset seen in out-patients in the USA. Early age at onset predicted a longer time to first pharmacological treatment (ρ =0.695, P <0.01).

Type
Short Report
Information
The British Journal of Psychiatry , Volume 194 , Issue 6 , June 2009 , pp. 559 - 560
Copyright
Copyright © Royal College of Psychiatrists, 2009 

Footnotes

Declaration of interest

None.

References

1 Post, RM, Luckenbaugh, DA, Leverich, GS, Altshuler, LL, Frye, MA, Suppes, T, et al. Incidence of childhood-onset bipolar illness in the USA and Europe. Br J Psychiatry 2008; 192: 150–1.Google Scholar
2 Leverich, GS, Post, RM. Course of bipolar illness after history of childhood trauma. Lancet 2006; 367: 1040–2.CrossRefGoogle ScholarPubMed
3 Leverich, GS, Post, RM, Keck, PE Jr, Altshuler, LL, Frye, MA, Kupka, RW, et al. The poor prognosis of childhood-onset bipolar disorder. J Pediatr 2007; 150: 485–90.Google Scholar
4 Geller, B, Craney, JL, Bolhofner, K, Nickelsburg, MJ, Williams, M, Zimerman, B. Two-year prospective follow-up of children with a prepubertal and early adolescent bipolar disorder phenotype. Am J Psychiatry 2002; 159: 927–33.Google Scholar
5 Perlis, RH, Miyahara, S, Marangell, LB, Wisniewski, SR, Ostacher, M, DelBello, MP, et al. Long-term implications of early onset in bipolar disorder: data from the first 1000 participants in the systematic treatment enhancement program for bipolar disorder (STEP–BD). Biol Psychiatr 2004; 55: 875–81.Google Scholar
6 Bennazzi, F, Akiskal, HS. How best to identify a bipolar-related subtype among major depressive patients without spontaneous hypomania: superiority of age at onset criterion over recurrence and polarity? J Affect Disord 2008; 107: 77–88.CrossRefGoogle Scholar
7 Rihmer, Z, Angst, J. Mood disorders: epidemiology. In Kaplan & Sadock's Comprehensive Textbook of Psychiatry (eds Sadock, BJ & Sadock, VA): 1575–82. Lippincott Williams & Wilkins, 2005.Google Scholar
8 American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders (4th edn) (DSM–IV). APA, 1994.Google Scholar
9 First, M, Spitzer, R, Gibbon, M, Williams, J. Structured Clinical Interview for DSM–IV – Patient Version. American Psychiatric Press, 1997.Google Scholar
10 Post, RM, Nolen, WA, Kupka, RW, Denicoff, KD, Leverich, GS, Keck, PE Jr, et al. The Stanley Foundation Bipolar Network: I. Rationale and methods. Br J Psychiatry 2001; 178 (suppl 41): s169–76.Google Scholar
11 Suppes, T, Leverich, GS, Keck, PE, Nolen, WA, Denicoff, KD, Altshuler, LL, et al. The Stanley Foundation Bipolar Treatment Outcome Network: II. Demographics and illness characteristics of the first 261 patients. J Affect Disord 2001; 67: 45–59.Google Scholar
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