Hostname: page-component-586b7cd67f-dsjbd Total loading time: 0 Render date: 2024-11-22T08:29:27.618Z Has data issue: false hasContentIssue false

The Use of LSD-25 as a Diagnostic Aid in Doubtful Cases of Schizophrenia

Published online by Cambridge University Press:  29 January 2018

J. C. Kenna
Affiliation:
University Department of Psychiatry, Manchester Royal Infirmary

Extract

In the course of studying the clinical effects of LSD-25 various workers have commented upon its possible use as an aid to psychiatric diagnosis. Stoll (1947) and Becker (1949) considered it to be of limited value in this respect. Condrau (1949) pointed out that it tended to exaggerate catatonic and hebephrenic features in schizophrenics and to produce a caricature of the personality in normal subjects; the latter point also being made by Anderson and Rawnsley (1954). Von Felsinger et al. (1956) considered the primary psychological effect of the drug to be an exacerbation of existing symptomatology, through a weakening of central functions and defence systems.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1965 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Anastasopoulos, G., and Photiades, H. (1962). “Effects of LSD-25 on relatives of schizophrenic patients.” J. Meat. Sci., 108, 9598.Google Scholar
Anderson, E. W., and Rawnsley, K. (1954). “Clinical studies of lysergic acid diethylamide.” Mschr. f. Psychiat. u. Neurol., 128, 3855.CrossRefGoogle Scholar
Becker, A. M. (1949). “Zur Psychopathologie der Lysergsäurediäthylamid-wirkung.” Wien. Z. Nervenheilk., 2, 402440.Google Scholar
Bleuler, E. (1911). Dementia Praecox or the Group of Schizophrenias (trans. Zinkin, J.). New York: Int. U.P. 1950.Google Scholar
Bruner, J. S. (1951). In Perception: an Approach to Personality (eds. Blake, R. R., and Ramsey, G. V.) New York: Ronald Press. p. 121.Google Scholar
Condrau, G. (1949). “Klinische Erfahrungen an Geisteskranken mit Lysergsäure-diäthylamid.” Acta. psychiat. neurol. scand., 24, 932.Google Scholar
Crocket, R., Sandison, R. A., and Walk, A. (1963). Hallucinogenic Drugs and their Psychotherapeutic Use. Proc. quarterly meeting of R.M.P.A., London, 1961. Lewis.Google Scholar
Delay, J., Pichot, P., and Lempérière, T. (1961). ‘The therapeutic implications of psilocybin’ in Hallucinogenic Drugs and their Psychotherapeutic Use (eds. Crocket, et al., London, 1963). Lewis.Google Scholar
Finney, D. J. (1948). “The Fisher-Yates Test of Significance in 2×2 Contingency Tables.” Biometrika, 35, 145156.Google Scholar
Grinker, R. R. (1963). “Lysergic acid diethylamide.” Arch. Gen. Psychiat., 8, 425.Google Scholar
Hunt, J. McV., and Guilford, J. P. (1933). “Fluctuation of ambiguous figures in dementia praecox and in manic depressive patients.” J. abnorm. soc. Psychol., 27, 443452.Google Scholar
Kretschmer, E. (1927). Der Sensitive Beziehungswahn. 3rd edition. 1950. Berlin: Springer.Google Scholar
Langfeldt, G. (1939). The Schizophreniform States. Copenhagen: Munksgaard.Google Scholar
Lino, T. M., and Buckman, H. (1960). “The use of lysergic acid in individual psychotherapy.” Proc. Roy. Soc. Med., 53, 927929.Google Scholar
Mayer-Gross, W. (1924). Selbstschilderungen der Verwirrtheit. Die oneiroide Erlebnisform. Berlin: Springer.CrossRefGoogle Scholar
Mayer-Gross, W. (Anderson, E. W.personal communication.)Google Scholar
Perez, P. (1961). “Size-constancy in normals and schizophrenics”, in Perceptual Changes in Psychopathology (eds. Ittelson, W. H., and Kutash, S. B.). Chap. 3, pp. 3955. New Brunswick: Rutgers U.P. 1961.Google Scholar
Rümke, H. C. (1957). ‘The clinical differentiation within the group of schizophrenics.’ 2nd Int. Congress of Psychiat., Zurich, 1957. Report 1 , 302. Orell Fussti.Google Scholar
Schneider, K. (1959). Clinical Psychopathology (trans. Hamilton, M. W.). New York: Grune & Stratton.Google Scholar
Siegel, S. (1956). Non-parametric Statistics for the Behavioural Sciences. New York: McGraw Hill.Google Scholar
Stoll, W. A. (1947). “Lysergsäure-diäthylamid, ein Phantastikum aus der Mutterkorngruppe.” Schweiz. Arch. f. Neurol. u. Psychiat., 60, 279323.Google Scholar
Von Felsinger, J., Lasagna, L., and Beecher, H. (1956). “The response of normal men to lysergic acid derivatives (di- and mono-ethyl amides).” J. Clin. Exp. Psychopath., 17, 414428.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.