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A Trial on Chronic Schizophrenic Patients of Oxypertine, a Psychotropic Drug with an Indole Ring

Published online by Cambridge University Press:  29 January 2018

J. Durell  and
W. Pollin
J. Durell
Affiliation:
Laboratoy of Clinical Sciences, National Institute of Mental Health, Bethesda 14, Maryland
W. Pollin
Affiliation:
Laboratoy of Clinical Sciences, National Institute of Mental Health, Bethesda 14, Maryland
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Extract

Previous studies from this laboratory have shown that loading with large doses of certain amino-acids and Marsilid produced marked behavioural change in some chronic schizophrenic patients (Pollin, Cardon and Kety, 1961). Methionine and tryptophane produced qualitatively different effects and there was no overlap between marked methionine and tryptophane reactors. The changes with tryptophane were characterized by mood elevation and increased involvement with the environment and extra-version, in several instances to a dramatic degree.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 109 , Issue 462 , September 1963 , pp. 687 - 691
Copyright
Copyright © Royal College of Psychiatrists, 1963 

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References

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