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Study of HLA Antigens Among Japanese Schizophrenics

Published online by Cambridge University Press:  29 January 2018

Akio Asaka ,
Yuji Okazaki ,
Ikuro Namura ,
Takeo Juji ,
Mitsuko Miyamoto  and
Bun-Noshin Ishikawa
Akio Asaka
Affiliation:
Institute of Brain Research, University of Tokyo School of Medicine, Bunkyo-ku, Tokyo, Japan
Yuji Okazaki
Affiliation:
Department of Neuropsychiatry, Tokyo University Hospital, Bunkyo-ku, Tokyo, Japan
Ikuro Namura
Affiliation:
Department of Neuropsychiatry, Tokyo University Hospital
Takeo Juji
Affiliation:
Blood Transfusion Service, Toyko University Hospital
Mitsuko Miyamoto
Affiliation:
Blood Transfusion Service, Tokyo University Hospital
Bun-Noshin Ishikawa
Affiliation:
Utsunomiya Mental Hospital, Utsunomiya City, Tochigi Prefecture, Japan
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Summary

HLA antigens were typed among 136 Japanese schizophrenics. Increased frequencies were seen in A9 (Aw24), A10 (A26) and Bw54, and decreased frequency in B40 antigens when compared to 187 Japanese controls. It is suggested that there may be an association between A9 (Aw24) and schizophrenia with a chronic-progressive course and also an association between A10 (A26) and hebephrenia.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 138 , Issue 6 , June 1981 , pp. 498 - 500
Copyright
Copyright © Royal College of Psychiatrists, 1981 

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References

Crowe, R. R. Thomson, J. S. Funk, R. & Weinberger, B. (1979) HLA antigens and schizophrenia. Archives of General Psychiatry, 36, 231–233.Google Scholar
Eberhard, G. Franzen, G. & Löw, B. (1975) Schizophrenia susceptibility and HLA antigens. Neuropsychobiology, 1, 211–217.Google Scholar
Ivanyi, D. Zemak, P. & Ivanyi, P. (1978) HLA antigens as possible markers of heterogeneity in schizophrenia. Journal of Immunogenetics, 5, 165–172.Google Scholar
Julien, R.-A. Mercier, P. Chouraqui, P. & Sutter, J.-M. (1978) Schizophrenics et antigèns d'histocompatibilité. L'Encéphale, IV, 99–113.Google Scholar
McGuffin, P., Farmer, A. E. & Rajah, S. M. (1978) Histocompatibility antigens and schizophrenia. British Journal of Psychiatry, 132, 149–151.Google Scholar
Miyamoto, M. & Juji, T. (1978) On the assessment of HLA antigens (in Japanese). The Journal of Clinical Science, 14, 751–755.Google Scholar
Sasazuki, T. McDevitt, H. O. & Grumet, F. C. (1977) The association between genes in the major histocompatibility complex and disease susceptibility. Annual Review of Medicine, 28, 425–452.CrossRefGoogle ScholarPubMed
Smeraldi, E. Bellodi, L. & Cazzullo, C. L. (1976) Further studies on the major histocompatibility complex as a genetic marker for schizophrenia. Biological Psychiatry, 11, 655–661.Google ScholarPubMed
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