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Sedative or Tranquillizer? A Comparison of the Hypnotic Effects of Chlordiazepoxide and Amylobarbitone Sodium

Published online by Cambridge University Press:  29 January 2018

Richard Perkins
Affiliation:
Academic Department of Psychiatry, Middlesex Hospital Medical School, London, W.1
John Hinton
Affiliation:
Academic Department of Psychiatry, Middlesex Hospital Medical School, London, W.1

Extract

Lader and Wing (1965) compared amylobarbitone sodium and chlordiazepoxide as daytime sedative drugs in anxious patients. Using a formal bioassay technique they found that 65 mg. of amylobarbitone sodium was equivalent to 9 mg. of chlordiazepoxide. Essential differences in the physiological and clinical actions of the drugs were not demonstrated, and the incidence of side effects, including drowsiness, was similar in each case.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1974 

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