Hostname: page-component-78c5997874-j824f Total loading time: 0 Render date: 2024-11-18T18:16:09.355Z Has data issue: false hasContentIssue false
  • English
  • Français

Schizophrenia: Initiation and Development

Published online by Cambridge University Press:  29 January 2018

P. R. J. Burch
P. R. J. Burch*
Affiliation:
Department of Medical Physics, The University of Leeds, The General Infirmary, Leeds, LS1 3EX
Get access Rights & Permissions [Opens in a new window]

Extract

According to a recent theory, schizophrenia is confined to people with a particular genetic predisposition and the disorder arises from a specific breakdown in the central part of the system that controls growth (Burch 1964, 1968). We call diseases of this general class autoaggressive. Their pathogenesis has two distinctive phases: initiation and development. Initiation, which is a purely random process, entails a form of spontaneous somatic gene mutation in growth-control stem cells.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 118 , Issue 545 , April 1971 , pp. 451 - 452
Copyright
Copyright © Royal College of Psychiatrists, 1971 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Abe, K. (1969). ‘The morbidity rate and environmental influence on monozygotic co-twins of schizophrenics.’ British Journal of Psychiatry, 115, 519–31.Google Scholar
Burch, P. R. J. (1964). ‘Schizophrenia: some new aetiological considerations.’ British Journal of Psychiatry, 110, 818–24.Google Scholar
Burch, P. R. J. (1968). An Inquiry Concerning Growth, Disease and Ageing. Edinburgh and Toronto.Google Scholar
Burch, P. R. J. and Rowell, N. R. (1970). ‘Lupus erythematosus. Analysis of the sex- and age-distributions of the discoid and systemic forms of the disease in different countries.’ Acta Dermato-venereologica, 50, 293–301.Google Scholar
Johnson, R. T., and Richardson, E. P. (1968). ‘The neurological manifestations of systemic lupus erythematosus.’ Medicine (Baltimore), 47, 337–69.CrossRefGoogle ScholarPubMed
Shields, J., Gottesman, I. J., and Slater, E. (1967). ‘Kallmann's 1946 schizophrenic twin study in the light of new information.’ Acta Psychiatrica Scandinavica, 43, 385–96.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.