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Prediction of Response to Electroconvulsive Therapy

Preliminary Validation of a Sign-Based Typology of Depression

Published online by Cambridge University Press:  02 January 2018

Ian Hickie*
Affiliation:
Mood Disorders Unit, Division of Psychiatry, Prince Henry Hospital, Sydney, 2036 Australia
Brian Parsonage
Affiliation:
Port Macquarie, Australia
Gordon Parker
Affiliation:
School of Psychiatry (University of New South Wales), Prince Henry Hospital, Sydney, Australia
*
Correspondence

Abstract

In an open study of 35 depressed patients, psychomotor disturbance, assessed by the CORE rating system, significantly predicted response to ECT in patients with a ‘retarded’ but not those with an ‘agitated’ type of illness. In multivariate analyses, psychomotor disturbance was the sole predictor of response. This preliminary study suggests that the CORE system, which has been shown to differentiate endogenous and non-endogenous depressive disorders, has predictive validity in relation to ECT response.

Type
Papers
Copyright
Copyright © The Royal College of Psychiatrists 

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