Article contents
A Mosaic Mongol with Normal Leucocyte Chromosomes
Published online by Cambridge University Press: 29 January 2018
Extract
The finding of chromosomal mosaicism in mongolism (Clarke et al., 1961) has added a new dimension to the problem of mongolism which has helped to answer some questions, but which has also created some new ones. It has been suggested that mosaicism may explain some of the microsymptoms of mongolism found in the siblings, parents and relatives of mongols. This has particular application to the increased atd angles on the palms of some mothers of mongols (Penrose, 1963).
- Type
- Research Article
- Information
- Copyright
- Copyright © Royal College of Psychiatrists, 1965
References
Blank, C. E., Gemmell, E., Casey, M. D., and Lord, M. (1962). “Mosaicism in a mother with a mongol child.”
Brit. med. J., ii, 378.Google Scholar
Clarke, C. M., Edwards, J. H., and Smallpeice, V. (1961). “21 Trisomy/normal mosaicism in an intelligent child with mongoloid characters.”
Lancet, i, 1028.Google Scholar
de Wolff, P. E., Schärer, K., and Lejeune, J. (1962). “Contribution a l'étude des jumeaux mongoliens. Un cas de monozygotisme hétérocaryote.”
Helv. Paediat. Acta, 17, 301.Google Scholar
Fitzgerald, P. H., and Lycette, R. R. (1961). “Mosaicism in man involving the autosome associated with mongolism.”
Heredity, 16, 509.Google Scholar
Gustavson, K.-H., and Ek, J. I. (1961). “Triple stem-line mosaicism in mongolism.”
Lancet, ii, 319.Google Scholar
Lindsten, J., Alvin, A., Gustavson, K.-H., and Fraccaro, M. (1962). “Chromosomal mosaic in a girl with some features of mongolism.”
Cytogenetics, i, 20.CrossRefGoogle Scholar
Nichols, W. W., Coriell, L. L., Fabrizio, D. P., Bishop, H. C., and Boggs, T. R. (1962). “Mongolism with mosaic chromosome pattern.”
J. Pediat., 60, 69.Google Scholar
Penrose, L. S. (1963). “Dermatoglyphs in mosaic mongolism and allied conditions.”
Abstracts XI International Congress of Genetics. September, 1963.Google Scholar
Smith, D. W., Therman, E. M., Patau, K., and Inhorn, S. L. (1963). “Mosaicism in mother of two mongoloids.”
Amer. J. Dis. Childh., 104, 534.Google Scholar
Valencia, J. I., de Lozzio, C. B., and de Coriat, L. F. (1963). “Heterosomic mosaicism in a mongoloid child.”
Lancet, ii, 488.Google Scholar
Verresen, H., van den Berghe, H., and Creemers, J. (1964). “Mosaic trisomy in phenotypically normal mother of mongol.”
Lancet, i, 526.Google Scholar
Weinstein, E. D., and Warkany, J. (1963). “Maternal mosaicism and Down's syndrome (mongolism).”
J. Pediat., 63, 599.Google Scholar
- 18
- Cited by
eLetters
No eLetters have been published for this article.