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Life-Threatening Allergic Reaction to Clozapine

Published online by Cambridge University Press:  02 January 2018

Gabriela Stoppe ,
Peter Müller ,
Thomas Fuchs  and
Eckart Rüther
Gabriela Stoppe*
Affiliation:
University of Goettingen, Department of Psychiatry, Von-Siebold-Str. 5, 3400 Goettingen, Germany
Peter Müller
Affiliation:
University of Goettingen, Department of Psychiatry, Von-Siebold-Str. 5, 3400 Goettingen, Germany
Thomas Fuchs
Affiliation:
University of Goettingen, Department of Dermatology, Von-Siebold-Str. 3, 3400 Goettingen, Germany
Eckart Rüther
Affiliation:
University of Goettingen, Department of Psychiatry, Von-Siebold-Str. 5, 3400 Goettingen, Germany
*
∗Correspondence
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Abstract

Clozapine, an ‘atypical’ antipsychotic drug, rarely induces allergic complications, which usually present as cutaneous reactions. We report the case of a 69-year-old woman, suffering from chronic schizophrenia, who developed an allergic asthmatic reaction following clozapine therapy. Intensive-care treatment was necessary. The reaction could be repeated by further exposure to the drug. Skin tests for hypersensitivity were negative.

Type
Brief Reports
Information
The British Journal of Psychiatry , Volume 161 , Issue 2 , August 1992 , pp. 259 - 261
Copyright
Copyright © 1992 The Royal College of Psychiatrists 

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