Hostname: page-component-cd9895bd7-7cvxr Total loading time: 0 Render date: 2024-12-31T20:31:01.110Z Has data issue: false hasContentIssue false
  • English
  • Français

Late-Life Depressive Disorder in the Community

I. the Relationship between MMSE score and Depression in Subjects with and Without Psychiatric History

Published online by Cambridge University Press:  02 January 2018

Rob Van Ojen ,
Chris Hooijer ,
Dick Bezemer ,
Cees Jonker ,
Jaap Lindeboom  and
Willem Van Tilburg
Get access Rights & Permissions [Opens in a new window]

Abstract

Background

In previous studies cognitive impairment in depressed elderly in-patients tends to be associated with a late onset of depression. This study tests the hypothesis that cognitive impairment is associated with depression only in elderly individuals with no history of psychiatric illness.

Method

We investigated an age-stratified sample of 4051 elderly people living in the community, aged between 65 and 84 (AMSTEL). The relationship between depression (GMS-AGECAT diagnosis) and scores on the Mini Mental State Examination was studied in subjects with and without a reported psychiatric history (CAMDEX questionnaire).

Results

Low MMSE scores (MMSE ≤ 25) were only associated with depression in subjects with no psychiatric history (young/old: OR = 2.75, 95% CI = 1.83, 4.19; old/old: OR = 2.21, 95% CI = 1.61, 3.03).

Conclusions

We concluded that the combination of cognitive impairment and first-episode depression in elderly individuals may indicate cerebral deterioration. Depression as such may not be associated with cognitive impairment.

Type
Papers
Information
The British Journal of Psychiatry , Volume 166 , Issue 3 , March 1995 , pp. 311 - 315
Copyright
Copyright © 1995 The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)
Submit a response

eLetters

No eLetters have been published for this article.