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Is Mania Incompatible with Down's Syndrome?

Published online by Cambridge University Press:  29 January 2018

Robert Sovner*
Affiliation:
Drug Intake Management and Evaluation System, Inc., 71 Elton Avenue, Watertown, Massachusetts 02172, U.S.A.
Anne Desnoyers Hurley
Affiliation:
Department of Psychology, Massachusetts Hospital School, Canton, Massachusetts, U.S.A.
Richard Labrie
Affiliation:
Drug Intake Management and Evaluation System, Inc.
*
Correspondence

Extract

In reviewing the medical literature on the association between affective illness and mental retardation (Sovner & Hurley, 1983), we were intrigued to find that, although there were many cases of major depression and depressive neurosis among people with Down's syndrome, there were no reports of mania in such individuals. This finding provoked us to pursue the hypothesis that Down's syndrome may preclude the development of mania.

Type
Research Article
Copyright
Copyright © 1985 The Royal College of Psychiatrists 

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