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II. The TRH Test

Published online by Cambridge University Press:  29 January 2018

Louise E. Braddock  and
Isabel M. Blake
Louise E. Braddock
Affiliation:
Oxford Rotational Training Scheme in Psychiatry
Isabel M. Blake
Affiliation:
University of Oxford, Department of Psychiatry, Littlemore Hospital Research Unit, Oxford, OX4 4XN
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Summary

Anterior pituitary response to TRH 200 μg i.v. was studied in ten chronic schizophrenic patients during long-term neuroleptic treatment. Nine patients had normal prolactin (PRL) response as compared with controls but in one the response was blunted; one patient had an exaggerated response. Prolactin increment was higher following TRH than haloperidol challenge. No growth hormone (GH) response to TRH was found and TSH responses were comparable to controls.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 139 , Issue 5 , November 1981 , pp. 404 - 407
Copyright
Copyright © Royal College of Psychiatrists, 1981 

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