Hostname: page-component-586b7cd67f-2plfb Total loading time: 0 Render date: 2024-11-29T02:21:32.586Z Has data issue: false hasContentIssue false
  • English
  • Français

Haloperidol in the Treatment of Children with Severe Behaviour Disorders

Published online by Cambridge University Press:  29 January 2018

M. A. Cunningham ,
V. Pillai  and
W. J. Blachford Rogers
M. A. Cunningham
Affiliation:
Department of Child Psychiatry, Crichton Royal, Dumfries
V. Pillai
Affiliation:
Department of Child Psychiatry, Royal Hospital for Sick Children, Glasgow; Children's Unit, The Pastures Hospital, Mickleover, Derby
W. J. Blachford Rogers
Affiliation:
Department of Child Psychiatry, Crichton Royal, Dumfries
Get access Rights & Permissions [Opens in a new window]

Extract

Since Janssen's (1959) introduction of haloperidol, numerous clinical trials have been published showing its usefulness in the treatment of mania and hypomanic states. Davies (1962) found it an effective drug in the treatment of adult patients showing aggressive behaviour resulting from various causes, and in the management of mania. Gerle (1963), in his review, showed the effectiveness of this drug in the control of disturbed behaviour in mentally sub-normal patients. He also showed (1962) that patients taking this drug are remarkably free from toxic reactions such as jaundice, agranulocytosis and allergic dermatitis. Haloperidol has been used in our unit (Rogers, 1955, 1965a) over the past three years. The impression has been gained that it controls aggressive, overactive and destructive behaviour in severely disturbed children, without impairing their ability to participate normally in the therapeutic activities of the unit (Rogers, 1965b).

Type
Research Article
Information
The British Journal of Psychiatry , Volume 114 , Issue 512 , July 1968 , pp. 845 - 854
Copyright
Copyright © Royal College of Psychiatrists, 1968 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Court, J. H., and Cameron, I. Q. (1963). “Psychomotor assessment of the effects of haloperidol” Perceptual and Motor Skills, 17, 168–170.CrossRefGoogle Scholar
Court, J. H. (1964). “A longitudinal study of psychomotor functioning in acute psychiatric patients” Brit. J. med. Psychol., 37, 167–173.Google Scholar
Davies, B. M. (1962). “Clinical observations on the therapeutic value of haloperidol” International Symposium on Haloperidol and Triperidol, November 1962, Milan, 299–303. Published by Instituto Luso Farmaco d'Italia.Google Scholar
Freedman, A. M., Effron, A. S., and Bender, L. (1955). “Pharmacotherapy in children with psychiatric illness” J. nerv. ment. Dis., 122, 479–486.Google Scholar
Gerle, B. (1962). “The occurrence of toxic side effects during treatment with haloperidol” International Symposium on Haloperidol and Triperidol. November 1962, Milan.Google Scholar
Gerle, B. (1963). “Control of disturbed behaviour in mentally subnormal patients” Acta psychiat. Scand., supplementum 169, 39, 348–350.Google Scholar
Haase, H. J., and Janssen, P. A. J. (1965). The Action of Neuroleptic Drugs. Amsterdam: North-Holland Publishing Co.Google Scholar
Hetherington, R. (1956). “The effects of E.C.T. on the efficiency and retentivity of depressed patients” Brit. J. med. Psychol., 29, 258–269.CrossRefGoogle Scholar
Janssen, P. A. J., et al. (1959). “Chemistry and pharmacology of C.N.S. depressants related to 4- (4-hydroxyphenylpiperidino) butyrophenone. I. Synthesis and screening data in mice” J. med. pharm. Chem., 1, 281–297.Google Scholar
Janssen, P. A. J. (1966). “The pharmacological and clinical mode of action of neuroleptic drugs” Clinical Trials Journal, 3, No. 1, 370–379.Google Scholar
Rey, A. (1934). “D'un procédé pour évaluer l'éducabilité” Arch. Psychol., Geneva, 24, 297–337.Google Scholar
Rogers, W. J. B. (1955). “A children's unit in a mental hospital. Treatment and research” Proc. Roy. Soc. Med., 48, 263–270.Google Scholar
Rogers, W. J. B. (1965a). “Children's in-patient psychiatric units.” In: Modern Perspectives in Child Psychiatry. (ed. Howells, John C.). 534–561. Edinburgh: Oliver & Boyd.Google Scholar
Rogers, W. J. B. (1956b). “Use of haloperidol in children's psychiatric disorders.” Clinical Trials Journal, 2, No. 2, 162–165.Google Scholar
Zangwill, O. L. (1946). “Some clinical applications of the Rev-Davis performance test.” J. ment. Sci., 92, 19–34.CrossRefGoogle Scholar
Submit a response

eLetters

No eLetters have been published for this article.