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A Genetic Study of Affective Disorder

Published online by Cambridge University Press:  29 January 2018

Geoffrey Hopkinson  and
Philip Ley
Geoffrey Hopkinson
Affiliation:
Department of Psychiatry, the University of Liverpool, 6 Abercromby Square, Liverpool 7
Philip Ley
Affiliation:
Department of Psychiatry, the University of Liverpool, 6 Abercromby Square, Liverpool 7
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Extract

It is well known that when affective illness has its onset in later life a family history of this illness is significantly less common than in cases where the onset is early. Thus, Kay (1959) compared cases in this respect before and after 60 years of age; the morbidity risk was 10–12·7 per cent for relatives of the early onset group and only 3·5–5·7 per cent in relatives of those falling ill for the first time after 60. Similarly, Hopkinson (1964), taking the age of 50 to divide his probands, found a significantly lower risk for affective illness in relatives of the older-onset probands.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 115 , Issue 525 , August 1969 , pp. 917 - 922
Copyright
Copyright © Royal College of Psychiatrists, 1969 

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