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Folnegović & Folnevogić-Šmalc's “Schizophrenia in Croatia: Inter-regional Differences in Prevalence and a Comment on Constant Incidence”

Published online by Cambridge University Press:  02 January 2018

Brian Cooper  and
John M. Eagles
Brian Cooper
Affiliation:
Department of Epidemiological Psychiatry, Zentralinstitut für Seelische Gesundheit, 6800 Mannheim, Germany, currently Section of Old Age Psychiatry, Institute of Psychiatry, London SE5 8AF
John M. Eagles
Affiliation:
Ross Clinic, Royal Cornhill Hospital, Cornhill Road, Aberdeen AB9 2ZF
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Abstract

“Study objective - The aim was to examine why differences exist in schizophrenia prevalence and risk in some areas of Croatia, when schizophrenia incidence rates do not appear to vary. Design - Areas differing by schizophrenia admission rates in patients born in 1953 and admitted by the age of 31 years are compared using a number of indicators relating both to general population characteristics and to those of schizophrenic cases in these populations. Setting - The study covers the whole of Croatia (4 601 469 inhabitants, 1981 census). Subjects - By the age of 31 years, out of 80 445 individuals born in Croatia in 1953, 464 were admitted for and diagnosed as having schizophrenia. Main results - Admission risk rates are higher in those parts of Croatia where emigration rates are high and lower where immigration rates are high. There is also a positive correlation with schizophrenia prevalence and manic depressive psychosis rates. There is a negative correlation with age of onset of schizophrenia and with schizophrenic reproduction rates. In the study areas, hospital incidence rates are not significantly different. Conclusions - Economic migration and negative selection in the domestic population are likely to be the most significant factors leading to differences in schizophrenia prevalence. The approximately equal incidence rates in the population, with different prevalence and admission risks, are linked to differences in the disease onset among schizophrenics with a positive family history for this condition. In other words, these patients, when part of the population with a greater prevalence and a greater hereditary loading, experience the onset more often at an earlier age. Thus they have a lower reproduction rate than in a population with a lower prevalence and a lower hereditary loading. Thus incidence rates in populations with different prevalences and different hereditary loads are maintained roughly equal over generations.”

Type
The Current Literature
Information
The British Journal of Psychiatry , Volume 164 , Issue 1 , January 1994 , pp. 97 - 100
Copyright
Copyright © The Royal College of Psychiatrists 

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References

Crocetti, G. M., Kulčnar, Ž., Kesić, B., et al (1964) Differential rates of schizophrenia in Croatia (Yugoslavia). American Journal of Public Health, 54, 196–206.Google Scholar
DeLisi, L. E. (1992) The significance of age of onset for schizophrenia. Schizophrenic Bulletin, 18, 209–215.Google Scholar
Der, G., Gupta, S. & Murray, R. M. (1990) Is schizophrenia disappearing? Lancet, 335, 513–516.Google Scholar
Eagles, J. M. & Whalley, L. J. (1985) Decline in the diagnosis of schizophrenia among first admissions to Scottish mental hospitals from 1969–78. British Journal of Psychiatry, 156, 368–372.Google Scholar
Folnegović, Z., Folnegović-Šmalc, V. & Kulćar, Z. (1990) The incidence of schizophrenia in Croatia. British Journal of Psychiatry, 156, 363–365.CrossRefGoogle ScholarPubMed
Folnegović, Z., Folnegović-Šmalc, V. (1992) Schizophrenia in Croatia: inter-regional differences in prevalence and comment on constant incidence. Journal of Epidemiology and Community Health, 46, 248–255.CrossRefGoogle Scholar
Folnegović-Šmalc, V., Folnegović, Z. & Kulćar, Z. (1990) Age of disease onset in Croatia's hospitalised schizophrenics. British Journal of Psychiatry, 156, 368–372.Google Scholar
Halldin, J. (1985) Prevalence of mental disorder in an urban population in central Sweden in relation to social class, marital status and immigration. Acta Psychiatrica Scandinavica, 71, 117–127.Google Scholar
Kesić, B., Kulćar, Ž., Kovaćić, L., et al (1981) Major results and their interpretation. In Epidemiology of Psychoses in Croatia (eds B. Kesić, Ž. Kulčar & P. V. Lemkau), pp. 122–164. Zagreb: Jugoslavenska Akademija Znanosti i Umjetnosti.Google Scholar
Lemkau, P. V., Kulčar, Ž., Kesić, B., et al (1980) Selected aspects of the epidemiology of psychoses in Croatia, Yugoslavia. IV: representative sample of Croatia and results of the survey. American Journal of Epidemiology, 122, 661–674.Google Scholar
Munk-Jorgenson, P. (1986) Decreasing first admission rates of schizophrenia among males in Denmark from 1970 to 1984: changing diagnostic patterns? Acta Psychiatrica Scandinavica, 73, 645–650.CrossRefGoogle Scholar
Murphy, H. B. M. (1977) Migration, culture and mental health. Psychological Medicine, 7, 677–684.Google Scholar
Torrey, E. F. (1987) Prevalence in schizophrenia. British Journal of Psychiatry, 150, 598–608.Google Scholar
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