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A Family Study of Two Subgroups of Schizoaffective Patients

Published online by Cambridge University Press:  02 January 2018

Mario Maj*
Affiliation:
Department of Psychiatry, First Medical School, University of Naples, Piazza Miraglia 2, I-80138 Napoli, Italy

Abstract

A family study was carried out in two groups of patients fulfilling RDC for schizoaffective disorder: in one, a full affective and a full schizophrenic syndrome were simultaneously present; in the other, affective and schizophrenic features appeared within a polymorphic and rapidly changing clinical picture, with depersonalisation/derealisation and/or confusion. In the first-degree relatives of patients of the former group, the risk of major psychiatric disorders was not significantly different from that of relatives of schizophrenics, whereas in the first-degree relatives of patients of the latter group a low risk for both schizophrenia and major affective disorders, and a relatively high risk for schizoaffective disorders, were observed.

Type
Papers
Copyright
Copyright © Royal College of Psychiatrists, 1989 

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References

Abrams, R. & Taylor, M. A. (1980) Importance of schizophrenic symptoms in the diagnosis of mania. American Journal of Psychiatry, 138, 658661.Google Scholar
Asberg, M., Montgomery, S. A., Perris, C., et al (1978) A comprehensive Psychopathological rating scale. Acta Psychiatrica Scandinavica (suppl. 271), 527.Google Scholar
Baron, M., Gruen, R., Asnis, J., et al (1982) Schizoaffective illness, schizophrenia and affective disorders. Morbidity risk and genetic transmission. Acta Psychiatrica Scandinavica, 65, 253262.Google Scholar
Endicott, J. & Spitzer, R. L. (1978) A diagnostic interview: the Schedule for Affective Disorders and Schizophrenia. Archives of General Psychiatry, 35, 837862.Google Scholar
Gershon, E. S., Hamovit, J., Guroff, J. J., et al (1982) A family study of schizoaffective, bipolar I, bipolar II, unipolar, and normal control probands. Archives of General Psychiatry, 39, 11571162.Google Scholar
Jaspers, K. (1962) General Psychopathology (trans Hoenig, J. & Hamilton, M. W.). Manchester: Manchester University Press.Google Scholar
Maj, M. (1988) Lithium prophylaxis of schizoaffective disorders: a prospective study. Journal of Affective Disorders, 14, 129135.CrossRefGoogle ScholarPubMed
Maj, M. & Perris, C. (1985) An approach to the diagnosis and classification of schizoaffective disorders for research purposes. Acta Psychiatrica Scandinavica, 72, 405417.CrossRefGoogle Scholar
Mendlewicz, J., Linkowski, P. & Wilmotte, J. (1980) Relationship between schizoaffective illness and affective disorders or schizophrenia: morbidity risk and genetic transmission. Journal of Affective Disorders, 2, 289302.Google Scholar
Mitsuda, H. (1965) The concept of “atypical psychoses” from the aspects of clinical genetics. Acta Psychiatrica Scandinavica, 41, 372377.Google Scholar
Perris, C. (1974) A study of cycloid psychoses. Acta Psychiatrica Scandinavica (suppl. 253), 178.Google Scholar
Pull, C. B., Pull, M. C. & Pichot, P. (1983) Nosological position of schizoaffective psychoses in France. Psychiatria Clinica, 16, 141148.Google Scholar
Spitzer, R. L., Endicott, J. & Robins, E. (1975) Research Diagnostic Criteria (RDC) for a Selected Group of Functional Disorders (2nd edn). New York: Biometrics Research.Google Scholar
Weinberg, W. (1925) Methoden und Technik der Statistik mit besonderer berucksichtigung der Sozialbiologie. In Handbuch der socialen Hygiene und Gersundheitsfursorge (eds Gottstein, A., Schlossman, A. & Teleky, L.). Berlin: Springer.Google Scholar
Williams, P. V. & McGlashan, T. H. (1987) Schizoaffective psychosis. Comparative long-term outcome. Archives of General Psychiatry, 44, 130137.Google Scholar
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