Hostname: page-component-586b7cd67f-rdxmf Total loading time: 0 Render date: 2024-11-25T20:15:11.934Z Has data issue: false hasContentIssue false

Effects of ECT and Depression on Various Aspects of Memory

Published online by Cambridge University Press:  29 January 2018

C. D. Frith
Affiliation:
South Cleveland Hospital, Middlesborough
Marilyn Stevens
Affiliation:
South Cleveland Hospital, Middlesborough
Eve C. Johnstone
Affiliation:
South Cleveland Hospital, Middlesborough
J. F. W. Deakin
Affiliation:
South Cleveland Hospital, Middlesborough
P. Lawler
Affiliation:
South Cleveland Hospital, Middlesborough
T. J. Crow
Affiliation:
Clinical Research Centre, Northwick Park Hospital, Watford Road, Harrow, Middlesex HA1 3UJ

Summary

Seventy severely depressed patients randomly assigned to receive 8 real or sham ECT were further subdivided on the basis of degree of recovery from depression afterwards. In comparison to a non-depressed control group the depressed patients were impaired on a wide range of tests of memory and concentration prior to treatment, but afterwards performance on most of the tests had improved. Real ECT induced impairments of concentration, short-term memory and learning, but significantly facilitated access to remote memories. At 6 month follow-up all differences between real and sham ECT groups had disappeared. On the majority of tests the previously depressed patients now performed at the same level as the control group. There was some evidence that a subgroup of treatment-resistant patients (poor outcome after real ECT) were significantly more likely to complain of memory problems 6 months later.

Type
Research Article
Copyright
Copyright © 1983 The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Baddeley, A. D. (1979) Working memory and reading. In Processing of Visible Language (eds. Kolers, P. A., Wrolstad, M. E. and Bouma, H.). Vol. I. New York: Plenum Press.Google Scholar
Bidder, T. G., Strain, L. J. & Brunschwig, L. (1970) Bilateral and unilateral ECT. Follow-up study and critique. American Journal of Psychiatry, 127, 737–45.Google Scholar
Carney, M. W. P., Roth, M. & Garside, R. F. (1965) The diagnosis of depressive syndromes and the prediction of ECT response. British Journal of Psychiatry, 111, 659–74.Google Scholar
Cronholm, B. & Ottosson, J.-O. (1963) The experience of memory after electroconvulsive therapy. British Journal of Psychiatry, 109, 251–8.Google Scholar
Cronin, D., Bodley, P., Potts, L., Mather, M. D., Gardner, R. K. & Tobin, J. C. (1970) Unilateral and bilateral ECT: a study of memory disturbance and relief from depression. Journal of Neurology, Neurosurgery and Psychiatry, 33, 705–13.CrossRefGoogle ScholarPubMed
Feighner, J. P., Robins, K., Guze, J. B., Woodruff, R. A., Winokur, G. & Munoz, R. (1972). Diagnostic criteria for use in psychiatric research. Archives of General Psychiatry, 26, 5763.CrossRefGoogle ScholarPubMed
Haliday, A. M., Davison, K., Brown, M. W. & Kreeger, L. C. (1968) A comparison of the effects on depression and memory of bilateral ECT and unilateral ECT to the dominant and non-dominant hemispheres. British Journal of Psychiatry, 114, 9971012.Google Scholar
Hamilton, M. (1967) Development of a rating scale for primary depressive illness. British Journal of Social and Clinical Psychology, 6, 278–96.Google Scholar
Johnstone, E. C., Deakin, J. F. W., Lawler, P., Frith, C. D., Stevens, M., McPherson, K. & Crow, T. J. (1980) The Northwick Park electroconvulsive therapy trial. The Lancet, 2, 1317–20.Google Scholar
Kornetsky, C. & Mirsky, A. F. (1966) On certain psychopharmacological and physiological differences between schizophrenics and normal persons. Psychopharmacologia, 8, 309–18.Google Scholar
Lloyd, G. G. & Lishman, W. A. (1975) Effect of depression on the speed of recall of pleasant and unpleasant experiences. Psychological Medicine, 5, 173–80.Google Scholar
Meddis, R. (1980) Unified analysis of variance by ranks. British Journal of Mathematical and Statistical Psychology, 33, 8494.Google Scholar
Medical Research Council (1965) Clinical Trial of the treatment of depressive illness. British Medical Journal, i, 881–6.Google Scholar
Pairio, A., Yuille, J. C. & Madigan, S. (1968) Concreteness, imagery and meaningfulness values for 925 nouns. Journal of Experimental Psychology. Monograph supplement, 76, 1 part 2.Google Scholar
Squire, L. R. & Chace, P. M. (1975) Memory functions six to nine months after electroconvulsive therapy. Archives of General Psychiatry, 32, 1557–64.Google Scholar
Sternberg, D. E. & Jarvik, M. E. (1976) Memory functions in depression. Archives of General Psychiatry, 33, 219–24.Google Scholar
Stevens, M. (1979) Famous personality test: a test for measuring remote memory. Bulletin of the British Psychological Society, 32, May 1979, 211 (proceedings of Annual Conference).Google Scholar
Teasdale, J. D. & Fogarty, S. J. (1979) Differential effects of induced mood on retrieval of pleasant and unpleasant events from episodic memory. Journal of Abnormal Psychology, 88, 248–57.Google Scholar
Warrington, E. K. & Silberstein, M. (1970) A questionnaire technique for investigating very long term memory. Quarterly Journal of Experimental Psychology, 22, 508–12.Google Scholar
Winer, B. J. (1971) Statistical Principles in Experimental Design. New York: McGraw-Hill.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.