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The Effect of Mild Hyperventilation on Red Cell Sodium

Published online by Cambridge University Press:  29 January 2018

J. Damas Mora ,
M. K. Patel  and
F. A. Jenner
J. Damas Mora
Affiliation:
University of Sheffield; Attached Worker of the MRC Unit for Metabolic Studies in Psychiatry, Sheffield S6 1TP
M. K. Patel
Affiliation:
University of Illinois Medical Center
F. A. Jenner
Affiliation:
University of Sheffield; Medical Research Council Unit for Metabolic Studies in Psychiatry, Sheffield S6 1TP
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Summary

Control subjects voluntarily overbreathed to produce end-tidal PCO2 levels similar to those found in patients suffering from neurotic or endogenous non-retarded depression. Red cell sodium content was found to decrease during overbreathing in all the subjects. The changes were similar to those usually reported for depressed patients.

The results imply that red cell sodium levels are in part dependent on respiratory behaviour. They suggest a need for considerable caution in interpreting red cell sodium values from psychiatric patients.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 130 , Issue 5 , May 1977 , pp. 459 - 462
Copyright
Copyright © Royal College of Psychiatrists, 1977 

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