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Effect of L-Triiodothyronine and Chlorpromazine on Ankle Reflex Time and a Clinical Thyroid Scale in Schizophrenics and Controls

Published online by Cambridge University Press:  29 January 2018

Eric D. West  and
C. J. S. Walter
Eric D. West
Affiliation:
Belmont Hospital, Sutton, Surrey
C. J. S. Walter
Affiliation:
St. Thomas' Hospital, S.E.1, and formerly Psychiatric Registrar, Belmont Hospital
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Extract

Claims have been made that thyroid hormone treatment benefits some schizophrenic patients. Earlier studies reported the use of dried thyroid in a dose of 48 gr. (2·9G) daily in a schizophrenic (Hoskins and Sleeper, 1929) and in other psychiatric states up to 60 gr. (3·6G) daily (Minski, 1927), but recent papers describe the use of l-triiodothyrgnine in place of dried thyroid in treating schizophrenics (Lochner, Scheuing and Flach, 1963; Flach, Celian and Rawson, 1958). Huxley, Mayr, Osmond and Hoffer (1964) believe that schizophrenics are more resistant to the effects of some physiological substances, including thyroxine, as part of a genetic polymorphism.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 114 , Issue 509 , April 1968 , pp. 451 - 457
Copyright
Copyright © Royal College of Psychiatrists, 1968 

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References

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