Hostname: page-component-586b7cd67f-r5fsc Total loading time: 0 Render date: 2024-11-25T23:02:32.105Z Has data issue: false hasContentIssue false
  • English
  • Français

Effect of Electroconvulsive Therapy on Erythrocyte Adenosine Triphosphatase Activity in Depressive Illness

Published online by Cambridge University Press:  29 January 2018

L. J. Whalley ,
M. Scott ,
H. W. Reading  and
J. E. Christie
L. J. Whalley
Affiliation:
MRC Brain Metabolism Unit, Thomas Clouston Clinic, 153, Morningside Drive, Edinburgh EH10 5LG
M. Scott
Affiliation:
MRC Brain Metabolism Unit, Thomas Clouston Clinic, 153, Morningside Drive, Edinburgh EH10 5LG
H. W. Reading
Affiliation:
MRC Brain Metabolism Unit, Thomas Clouston Clinic, 153, Morningside Drive, Edinburgh EH10 5LG
J. E. Christie
Affiliation:
MRC Brain Metabolism Unit, Thomas Clouston Clinic, 153, Morningside Drive, Edinburgh EH10 5LG
Get access Rights & Permissions [Opens in a new window]

Summary

Erythrocyte membrane adenosine triphosphatase activities were examined in twelve unipolar depressed patients receiving ECT. Eleven patients undergoing diagnostic cystoscopy served as controls for the acute effects of anaesthesia, and sixteen healthy subjects served as non-depressed controls. The unipolar depressed patients had a slight reduction in their (Na++K+)-ATPase activity but effective ECT treatment was not associated with any increase in this activity. This approach is unlikely to cast further light on the membrane phenomenology of depressive illness.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 137 , Issue 4 , October 1980 , pp. 343 - 345
Copyright
Copyright © Royal College of Psychiatrists, 1980 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Choi, S. J., Taylor, M. A. & Abrams, R. (1977) Depression, ECT and erythrocyte adenosine triphosphatase activity. Biological Psychiatry, 12, 75–81.Google Scholar
Dick, D. A. T., Dick, E. G., Le Poidevin, D. & Naylor, G. J. (1972) Sodium and potassium transport in depressive illness. Journal of Physiology, 227, 30–2.Google Scholar
Hamilton, M. (1960) A rating scale for depression. Journal of Neurology, Neurosurgery and Psychiatry, 23, 56–62.Google Scholar
Hesketh, J. E. (1976) Changes in membrane adenosine triphosphatase on administration of lithium salts in vivo. Biochemical Society Transactions, 4, 328–30.CrossRefGoogle ScholarPubMed
Hesketh, J. E., Glen, A. I. M. & Reading, H. W. (1977) Membrane ATPase and activities in depressive illness. Journal of Neurochemistry, 28, 1401–2.Google Scholar
Hesketh, J. E., Loudon, J. B., Reading, H. W. & Glen, A. I. M. (1978) The effect of lithium treatment on erythrocyte membrane ATPase activities and erythrocyte ion content. British Journal of Clinical Pharmacology, 5, 323–9.Google Scholar
Naylor, G. J., Dick, D. A. T., Dick, E. G., Le Poidevin, D. & Whyte, S. F. (1973) Erythrocyte membrane cation carrier in depressive illness. Psychological Medicine, 3, 502–8.CrossRefGoogle ScholarPubMed
Scott, M. & Reading, H. W. (1978) A comparison of platelet membrane and erythrocyte membrane adenosine triphosphatase specific activities in affective disorders. Biochemical Society Transactions, 6, 642–4.Google Scholar
Whalley, L. J., Yates, C. M. & Christie, J. E. (1980) Effect of electroconvulsive therapy (ECT) on plasma tryptophan. Psychological Medicine, 10, 377–80.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.