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‘Early-Onset Schizophrenia’ After Teenage Head Injury

A Case Report with Magnetic Resonance Imaging

Published online by Cambridge University Press:  02 January 2018

Eadbhard O'Callaghan
Affiliation:
Cluain Mhuire Family Centre, Blackrock, County Dublin
Conall Larkin
Affiliation:
Cluain Mhuire Family Centre, Blackrock, County Dublin
Oonagh Redmond
Affiliation:
Institute of Radiological Sciences, Mater Hospital, Dublin
John Stack
Affiliation:
Institute of Radiological Sciences, Mater Hospital, Dublin
Joseph T. Ennis
Affiliation:
Institute of Radiological Sciences, Mater Hospital, Dublin
John L. Waddington*
Affiliation:
Royal College of Surgeons in Ireland, Dublin
*
Royal College of Surgeons in Ireland, St Stephen's Green, Dublin 2, Ireland

Abstract

A 14–year-old youth sustained an Injury to the left frontoparietal area, which was followed by evident change in personality and subsequently by an early-onset schizophrenia-like psychosis. Magnetic resonance imaging revealed ventricular dilatation, slightly more marked in the left hemisphere, and cortical atrophy. Some implications of this case for research on schizophrenia itself are discussed.

Type
Brief Reports
Copyright
Copyright © Royal College of Psychiatrists, 1988 

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References

Andreasen, N., Nasrallah, H. A., Dunn, V., Olson, S. C., Grove, W. M., Ehrhardt, J. C., Coffman, J. A. & Crossett, J. H. W. (1986) Structural abnormalities in the frontal system in schizophrenia: a magnetic resonance imaging study. Archives of General Psychiatry, 43, 136144.CrossRefGoogle ScholarPubMed
Cramer, G. D., Allen, D. J., Didio, L. J. A., Potvin, W. & Brinker, R. (1987) Quantification of cerebral ventricular volume using magnetic resonance imaging (MRI) in thirty nine human subjects without apparent pathology. Society for Neuroscience Abstracts, 13, 1627.Google Scholar
Crow, T. J. (1986) Left brain, retrotransposons and schizophrenia. British Medical Journal, 293, 34.CrossRefGoogle ScholarPubMed
Johnstone, E. C., Crow, T. J., Frith, C. D., Husband, J. & Kreel, L. (1976) Cerebral ventricular size and cognitive impairment in schizophrenia. The Lancet, ii, 924926.CrossRefGoogle Scholar
Kendler, K. S., Tsuang, M. T. & Hays, P. (1987) Age at onset in schizophrenia: a familial perspective. Archives of General Psychiatry, 44, 881890.CrossRefGoogle ScholarPubMed
The Lancet (1987) Schizophrenia and organic disease (editorial). The Lancet, ii, 776777.Google Scholar
Lewis, S. W., Reveley, A. M., Reveley, M. A., Chitkara, B. & Murray, R. M. (1987) The familial/sporadic distinction as a strategy in schizophrenia research. British Journal of Psychiatry, 151, 306313.CrossRefGoogle ScholarPubMed
Murray, R. M., Lewis, S. W. & Reveley, A. M. (1985) Towards an aetiological classification of schizophrenia. The Lancet, i, 10231026.CrossRefGoogle Scholar
Shelton, R. C. & Weinberger, D. R. (1986) X-ray computerised tomography studies of schizophrenia: a review and synthesis. In The Neurology of Schizophrenia (eds Nasrallah, H. A. & Weinberger, D. R.). Amsterdam: Elsevier.Google Scholar
Weinberger, D. R. (1987) Implications of normal brain development for the pathogenesis of schizophrenia. Archives of General Psychiatry, 44, 660669.CrossRefGoogle ScholarPubMed
Weinberger, D. R., Berman, K. F. & Zec, R. F. (1986) Physiological dysfunction of dorsolateral prefrontal cortex in schizophrenia. I. Regional cerebral blood flow evidence. Archives of General Psychiatry, 43, 114124.CrossRefGoogle ScholarPubMed
Wilcox, J. A. & Nasrallah, H. A. (1987) Childhood head trauma and psychosis. Psychiatry Research, 21, 303306.CrossRefGoogle ScholarPubMed
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