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Diencephalic Stimulation and the Effects of Ect in Endogenous Depression

Published online by Cambridge University Press:  29 January 2018

Richard Abrams
Affiliation:
Department of Psychiatry and Behavioral Sciences, University of Health Sciences/The Chicago Medical School; formerly at the Department of Psychiatry and Behavioral Sciences, State University of New York at Stony Brook
Michael Alan Taylor
Affiliation:
Department of Psychiatry and Behavioral Sciences, University of Health Sciences/The Chicago Medical School; formerly at the Department of Psychiatry and Behavioral Sciences, State University of New York at Stony Brook

Summary

We compared conventional bilateral ECT treatment electrode placement with simultaneous unilateral electrode placement to both sides of the head (dominant/nondominant unilateral ECT) in 20 patients with endogenous depression. Under double-blind random assignment conditions we found that six bilateral ECT were significantly more effective than six dominant/nondominant unilateral ECT in reducing depression rating scale scores. In the light of data from intracerebral ECT current distribution studies we interpret our findings to support our previously advanced hypothesis that diencephalic stimulation is requisite for the therapeutic benefit of bilateral ECT in endogenous depression.

Type
Papers
Copyright
Copyright © Royal College of Psychiatrists, 1976 

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References

Abrams, R. (1975) What's new in convulsive therapy? In New Dimensions in Psychiatry: A World View (ed Arieti, ). New York.Google Scholar
Abrams, R., Fink, M., Dornbush, R., Feldstein, S., Volavka, J. & roubicek, J. (1972) Unilateral and bilateral electroconvulsive therapy: effects on depression, memory, and the electroencephalogram. Archives of General Psychiatry, 27, 8891.CrossRefGoogle ScholarPubMed
Abrams, R. & Taylor, M. (1973) Anterior bifrontal ECT: a clinical trial. British Journal of Psychiatry, 122, 587—90.CrossRefGoogle ScholarPubMed
Abrams, R. & Taylor, M. (1974) Electroconvulsive therapy and the diencephalon: a preliminary report. Comprehensive Psychiatry, 15, 233—6.CrossRefGoogle ScholarPubMed
Abrams, R. Volavka, J. & Fink, M. (1973) EEG seizure patterns during multiple unilateral and bilateral ECT. Comprehensive Psychiatry, 14, 25—8.Google Scholar
Abrams, R. Volavka, Roubicek, J.J., Dornbush, R. & Fink, M. (1970) Lateralized EEG changes after unilateral and bilateral electroconvulsive therapy. Diseases of the Nervous System GWAN Supplement, 31, 2833.Google Scholar
Carney, M. W. P. & Sheffield, B. F. (1973) Electroconvulsive therapy and the diencephalon. Lancet, i, 1505.Google Scholar
Cohen, B. D., Noblin, C. D. & Silverman, A. J. (1968) Functional asymmetry of the human brain Science, 162, 475—7.CrossRefGoogle ScholarPubMed
Hamilton, M. (1960) A rating scale for depression. Journal of Neurology Neurosurgery and Psychiatry, 23, 5662.Google Scholar
Hayes, K. J. (1950) The current path in electroconvulsion shock. Archives of Neurology and Psychiatry, 63, 102—9.CrossRefGoogle Scholar
Nauta, W. J. H. (1971) The problem of the frontal lobe: a reinterpretation. Journal of Psychiatric Research, 8, 167—87.Google Scholar
Ottoson, J. O. (1960) Experimental studies of the mode of action of electroconvulsive therapy. Acta Psychiatrica et Neurologica Scandinavica, Supplementum 145 ad vol. 35, 5141.Google Scholar
Pollitt, J. D. (1965) Suggestions for a physiological classification of depression. British Journal of Psychiatry 111, 489—95.Google Scholar
Small, J. G. (1974) EEG and neurophysiological studies of convulsive therapies. In Psychobiology of Convulsive Therapy (eds Fink, Kety, McGraw, Williams). Washington.Google Scholar
Smitt, J. W. & Wegener, C. F. (1944) On electric convulsive therapy. Acta Psychiatrica et Neurologica Scandinavica, 19, 529—49.CrossRefGoogle Scholar
Volavka, J., Feldstein, S., Abrams, R., Dornbush, R. & Fink, M. (1972) EEG and clinical change after bilateral and unilateral electroconvulsive therapy. Electroencephalography and Clinical Neurophysiology 32, 631—9.CrossRefGoogle ScholarPubMed
Weaver, L., Williams, R. & Rush, S. (1976) Current density in bilateral and unilateral ECT. Biological Psychiatry, 11, 303—12Google ScholarPubMed
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