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A Danish Twin Study of Schizophrenia

Published online by Cambridge University Press:  29 January 2018

Margit Fischer ,
B. Harvald  and
M. Hauge
Margit Fischer
Affiliation:
Psychiatric Research Department, University of Aarhus, State Hospital, Risskov, and the Danish Twin Register, Institute of Medical Genetics, University of Copenhagen, Denmark
B. Harvald
Affiliation:
Psychiatric Research Department, University of Aarhus, State Hospital, Risskov, and the Danish Twin Register, Institute of Medical Genetics, University of Copenhagen, Denmark
M. Hauge
Affiliation:
Psychiatric Research Department, University of Aarhus, State Hospital, Risskov, and the Danish Twin Register, Institute of Medical Genetics, University of Copenhagen, Denmark
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Extract

Previous studies on schizophrenia in twins have quite recently been reviewed in detail by Gottesman and Shields (1966a) and Shields (1968). The indications of concordance in different series are highly diverging, in monozygotic pairs ranging from near unity to zero. The high concordance rates found by Luxenburger (1928), Kallmann (1946) and Slater (1953) stress the importance of genetic factors in the aetiology of schizophrenia, whereas the low concordance rate in two recent Scandinavian twin series (Tienari, 1963; Kringlen, 1966) has given rise to the question whether special genetic or environmental factors prevail in some populations. It has, therefore, been found of interest to study schizophrenia in a Danish twin population.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 115 , Issue 526 , September 1969 , pp. 981 - 990
Copyright
Copyright © Royal College of Psychiatrists, 1969 

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References

Allen, G., Harvald, B., and Shields, J. (1967). “Measures of twin concordance.” Acta genet. (Basel), 17, 475–81.Google Scholar
Essen-Möller, E. (1941). Psychiatrische Untersuchungen an einer Serie von Zwillingen. Copenhagen: Munksgård.Google Scholar
Fremming, K. (1947). Morbid Risk of Mental Diseases and other Abnormal Psychic States among Average Danish Populations. Copenhagen: Munksgård.Google Scholar
Gottesman, I. I., and Shields, J. (1966a). “Contributions of twin studies to perspectives in schizophrenia.” In: Maher, B. A. (ed.): Progress in Experimental Personality Research. Vol. 3, pp. 1–84. New York: Academic Press.Google Scholar
Gottesman, I. I., and Shields, J. (1966b). “Schizophrenia in twins: 16 years consecutive admissions to a psychiatric clinic.” Brit. J. Psychiat., 112, 809–18.CrossRefGoogle Scholar
Hauge, M., Harvald, B., Fischer, Margit, Gotlieb Jensen, K., Juel-Nielsen, N., Raebild, Ingrid, Shapiro, R., and Videbech, T. (1968). “The Danish twin register.” Acta genet. med. (Roma), 17, (in Press).Google Scholar
Inouye, E. (1963). “Similarity and dissimilarity of schizophrenia in twins.” Proceedings of the Third World Congress on Psychiatry. Vol. 1, pp. 524–30. Montreal: University of Toronto Press.Google Scholar
Kallman, F. J. (1946). “The genetic theory of schizophrenia. An analysis of 794 twin index families.” Amer. J. Psychiat., 103, 309–22.CrossRefGoogle Scholar
Kringlen, E. (1966). “Schizophrenia in twins. An epidemiological-clinical study.” Psychiatry, 29, 172–84.CrossRefGoogle Scholar
Luxenburger, H. (1928). “Vorläufiger Bericht über psychiatrischen Serieuntersuchungen an Zwillingen.” Z. ges. Neurol. Psychiat., 176, 297–326.CrossRefGoogle Scholar
Rosanoff, A. J., Handy, I. M., Plesset, I. R., and Brush, S. (1934). “The etiology of so-called schizophrenic psychoses. With special reference to their occurrence in twins.” Amer J. Psychiat., 91, 247–86.CrossRefGoogle Scholar
Shields, J. (1968). “Summary of the genetic evidence.” J. psychiat. Res., Vol. Suppl., 95–126.CrossRefGoogle Scholar
Slater, E. (1953). Psychotic and Neurotic Illnesses in Twins. Her Majesty's Stationery Office, London.Google ScholarPubMed
Tienari, P. (1963). “Psychiatric illnesses in identical twins.” Acta psychiat. Scand., Suppl. 171, pp. 1–195.Google Scholar
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