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A Controlled Study of Lithium vs. Chlorpromazine in Acute Schizophrenics

Published online by Cambridge University Press:  29 January 2018

Baron Shopsin ,
Suk Sik Kim  and
Samuel Gershon
Baron Shopsin
Affiliation:
Neuropsychopharmacology Research Unit, Department of Psychiatry, New York University Medical Center, New York, N.Y. 100016, U.S.A.
Suk Sik Kim
Affiliation:
Manhattan State Hospital, New York
Samuel Gershon
Affiliation:
Neuropsychopharmacology Research Unit, Department of Psychiatry, New York University Medical Center, New York, N.Y. 10016, U.S.A.
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Extract

A previous double-blind controlled evaluation of lithium and chlorpromazine in both manic and schizo-affective individuals carried out in this unit (Johnson et al., 1968) indicated that 85 per cent of the schizo-affectives showed a worsening of thought disorder when treated with lithium carbonate, the majority developing symptoms of an acute brain syndrome. The possibility of experimental design accounting for such treatment outcome must be considered.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 119 , Issue 551 , October 1971 , pp. 435 - 440
Copyright
Copyright © The Royal College of Psychiatrists, 1971 

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