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A Controlled Physiological, Clinical and Psychological Evaluation of Chlordiazepoxide

Published online by Cambridge University Press:  29 January 2018

Desmond Kelly ,
Clinton C. Brown  and
John W. Shaffer
Desmond Kelly
Affiliation:
Nuffield Foundation Medical Fellow, and Chief Assistant, Department of Psychiatry, St. Thomas's Hospital, London S.E.1
Clinton C. Brown
Affiliation:
Associate Professor of Medical Psychology
John W. Shaffer
Affiliation:
Assistant Professor of Medical Psychology The Henry Phipps Psychiatric Clinic, The Johns Hopkins Hospital, Baltimore, Maryland, U.S.A.
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Extract

“Much doubt persists about the different benefits from, and indications for, all the many drugs proposed for the relief of anxiety” (Lancet, 1965). Chlordiazepoxide is one of the most popular minor tranquillizers used by psychiatrists, physicians and general practitioners. Its efficacy has been advocated in the “Today's Drugs” column of the British Medical Journal (1967, 1968a and b). Others, however, have been “impressed by the number of patients who claim great benefit but show little evidence of this” (Jenner, 1965).

Type
Research Article
Information
The British Journal of Psychiatry , Volume 115 , Issue 529 , December 1969 , pp. 1387 - 1392
Copyright
Copyright © Royal College of Psychiatrists, 1969 

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References

Bargroft, H., and Swan, H. J. C. (1953). Sympathetic Control of Human Blood Vessels, London.Google Scholar
Brit. med. J. (1967). “Benzodiazepines.” ii, 36–8.Google Scholar
Brit. med. J. (1968a). “Tranquillizers.” ii, 230–1.Google Scholar
Brit. med. J. (1968b). “Treatment of psychoneurosis.” ii, 288–9.Google Scholar
Clancy, J., and Vanderhoof, E. (1963). “Physiologic responses in therapeutic relationships.” Dis. nerv. Syst. Google Scholar
Clyde, D. J. (1963). Manual for the Clyde Mood Scale. University of Miami.Google Scholar
de la Lande, I. S., and Whelan, R. F. (1959). “The effect of antagonists on the response of the forearm vessels to adrenaline.” J. Physiol. (Lond.) 148, 548–53.Google Scholar
Edwards, A. L. (1960). Experimental Design in Psychological Research, New York.Google Scholar
Jenner, F. A. (1965). “Use of drugs in anxiety states.” In: Scientific Basis of Drug Therapy in Psychiatry, ed. Marks, J., and Pare, C. M. B. Oxford.Google Scholar
Kelly, D. H. W. (1966). “Measurement of anxiety by forearm blood flow.” Brit. J. Psychiat., 112, 789–98.Google Scholar
Kelly, D. H. W. (1967). “The technique of forearm plethysmography for assessing anxiety.” J. psychosom. Res., 10, 373–82.CrossRefGoogle Scholar
Kelly, D. H. W., Brown, C. C, and Shaffer, J. W. (1969). “A comparison of physiological and psychological measurements on anxious patients and normal controls.” Psychophysiology (In press).Google Scholar
Kelly, D. H. W., Walter, G. J. S., and Sargant, W. (1966). “Modified leucotomy assessed by forearm blood flow and other measurements.” Brit.J. Psychiat., 112, 871–81.Google Scholar
Kelly, D. H. W., Walter, G. J. S. (1968). “The relationship between clinical diagnosis and anxiety assessed by forearm blood flow and other measurements.” Ibid., 114, 611–26.Google Scholar
Kelly, D. H. W., Walter, G. J. S. (1969). “A clinical and physiological relationship between anxiety and depression.” Ibid., 115, 401–6.Google Scholar
Lader, M. H., and Wing, L. (1966). Physiological Measures, Sedative Drugs and Morbid Anxiety, London.Google Scholar
Lancet (1965). “Comparison of barbiturates in anxiety.” i, 1107–8.Google Scholar
Osgood, G. E., Suci, G. J., and Tannenbaum, P. H. (1957). The Measurement of Meaning, Illinois.Google Scholar
Zung, W. W. K. (1965). “A self-rating depression scale.” Arch. gen. Psychiat., 12, 63–70.Google Scholar
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