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“Continuous” Thioproperazine

A Controlled Trial in Chronic Schizophrenia

Published online by Cambridge University Press:  29 January 2018

E. C. MacLeod
Affiliation:
Department of Psychological Medicine, Southern General Hospital, Glasgow; Glasgow Royal Mental Hospital
J. Moffat
Affiliation:
Glasgow Royal Mental Hospital

Extract

Thioproperazine (‘Majeptil’) is a recently introduced phenothiazine derivative which readily produces extra-pyramidal disturbances. Its pharmacology was originally described by Courvoisier et al. (1958) and its clinical properties by a number of workers including, in this country, Denham and Carrick (1961). Several investigators have reported impressive results with this drug in a variety of mentally ill patients, including chronic schizophrenics who had failed to respond to other forms of therapy.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1963

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