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A Comparison of Subjective Responses to Imipramine and Tranylcypromine

Published online by Cambridge University Press:  29 January 2018

F. G. Spear ,
P. Hall  and
J. D. Stirland
F. G. Spear
Affiliation:
Department of Psychiatry, Sheffield University and United Hospitals
P. Hall
Affiliation:
Department of Psychiatry, Sheffield University and United Hospitals
J. D. Stirland
Affiliation:
Department of Psychiatry, Sheffield University and United Hospitals
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Extract

Although the number of anti-depressant drugs available has grown rapidly in recent years, they are still broadly classified into three main groups. First are the general nervous system stimulants, exemplified by amphetamine, second the group derived from the phenothiazines exemplified by imipramine and third, the monoamineoxidase inhibitors—the first example of which was iproniazid. The general stimulants have many disadvantages, their place in treatment is limited, but fairly well defined. Many monoamineoxidase inhibitors have been found to have serious toxic effects, but some, including tranylcypromine appear to be reasonably safe and effective (Agin, 1960).

Type
Research Article
Information
The British Journal of Psychiatry , Volume 110 , Issue 464 , January 1964 , pp. 53 - 55
Copyright
Copyright © Royal College of Psychiatrists, 1964 

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References

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Spear, F. G., m.b., ch.b., d.p.m., Senior Registrar Google Scholar
Hall, P., m.b., ch.b., ph.d., d.p.m., Late Foundations Fund Research Fellow∗ Google Scholar
Stirland, J. D., b.a., m.b., b.chir., d.p.m., Senior Registrar Department of Psychiatry, Sheffield University and United Hospitals Google Scholar
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