Hostname: page-component-586b7cd67f-g8jcs Total loading time: 0 Render date: 2024-11-25T20:56:23.495Z Has data issue: false hasContentIssue false

A Comparison of Nortriptyline and Amitriptyline in Depression

Published online by Cambridge University Press:  29 January 2018

John T. Rose
Affiliation:
Walton Hospital, Liverpool
M. R. Leahy
Affiliation:
St. James's Hospital, Leeds
Ian C. A. Martin
Affiliation:
St. James's Hospital, Leeds
T. T. Westhead
Affiliation:
Walton Hospital, Liverpool

Extract

Nortriptyline (Allegron, Aventyl) is the demethylated metabolite of amitriptyline. Preliminary trials by Bennett (1962), Oltman et al. (1963) and Leahy et al. (1964) indicated that it might be an effective anti-depressant. Forrest et al. (1964) found that it compared favourably with amitriptyline, a widely used anti-depressant of established efficacy. This investigation also compares nortriptyline with amitriptyline.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1965 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bennett, I. F. (1962). J. nerv. ment. Dis., 135, 58.CrossRefGoogle Scholar
Forrest, A. D., Affleck, J. W. McL., Gibb, I. A., and Priest, R. G. (1964). Scot. med. J., 9, 341.Google Scholar
Hamilton, M. (1960). J. Neurol. Neurosurg. Psychiat., 23, 56.Google Scholar
Leahy, M. R., and Rose, J. T. (1964). Am. J. Psychiat., 121, 72.Google Scholar
Oltman, J. E., and Friedman, S. (1963). Am. J. Psychiat., 119, 988.CrossRefGoogle Scholar
Submit a response

eLetters

No eLetters have been published for this article.