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A Comparison of Doctor and Patient Improvement Ratings in a Drug (Meprobamate) Trial

Published online by Cambridge University Press:  29 January 2018

Lee C. Park
Affiliation:
Johns Hopkins University School of Medicine, Baltimore, Maryland
Eberhard H. Uhlenhuth
Affiliation:
Johns Hopkins University School of Medicine, Baltimore, Maryland
Ronald S. Lipman
Affiliation:
Psychopharmacology Service Center, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland
Karl Rickels
Affiliation:
School of Medicine, University of Pennsylvania, and Director of Psychopharmacological Research, Philadelphia General Hospital, Philadelphia, Pennsylvania
Seymour Fisher
Affiliation:
Psychopharmacology Laboratory, Division of Psychiatry, Boston University School of Medicine, Boston, Massachusetts

Extract

Out-patient drug trials have relied largely on observer-rated improvement measures to evaluate the efficacy of psychotropic medication (4). Less frequent use (5, 7, 9) has been made of patient ratings or the combination of observer plus patient ratings. Thus a comparison of improvement ratings made by the patient and his treating doctor would be of considerable methodological interest.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1965 

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References

1 Edwards, Allen L. (1950). Experimental Design in Psychological Research. New York: Rinehart and Co., Inc.Google Scholar
2 Fisher, S., Cole, J. O., Rickels, K., and Uhlenhuth, E. H. (1962). “Drug-set inter-action: the effect of expectations on drug response in out-patients.” In Neuro-Psychopharmacology (eds. Bradley, P. B., Flügel, F., and Hoch, P.) Amsterdam: Elsevier Pub. Co.Google Scholar
3 Frank, Jerome D., Gliedman, Lester H., Imber, Stanley D., and Nash, Earl H. (1957). “Why patients leave psychotherapy.” A.M.A. Arch. Neurol. Psychiat., 77, 283299.CrossRefGoogle Scholar
4 Lorr, Maurice (1960). “Rating scales, behavior inventories and drugs”, in Drugs and Behavior (eds. Uhr, Leonard and Miller, James G.). New York and London: John Wiley and Sons, Inc.Google Scholar
5 Lorr, Maurice, McNair, Douglas M., and Weinstein, George J. (1963). “Early effects of chlordiazepoxide (Librium) used with psychotherapy.” J. Psychiat. Res., 1, 257270.CrossRefGoogle Scholar
6 Parloff, Morris B., Kelman, Herbert C., and Frank, Jerome D. (1954). “Comfort, effectiveness and self-awareness as criteria of improvement in psychotherapy. Amer. J. Psychiat., 111, 343351.CrossRefGoogle ScholarPubMed
7 Rickels, Karl, Clark, Thomas W., Ewing, James H., and Klingensmtth, Walter C. (1959). “Evaluation of tranquilizing drugs in medical out-patients.” J.A.M.A., 171, 16491656.CrossRefGoogle Scholar
8 Siegel, Sidney (1956). Nonparametric Statistics for the Behavioral Sciences. New York: McGraw-Hill Book Company, Inc.Google Scholar
9 Uhlenhuth, E. H., and Park, Lee C. (1964). “The influence of medication (imipramine) and doctor in relieving depressed psycho-neurotic out-patients.” J. Psychiat. Res., 2, 101122.CrossRefGoogle Scholar
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