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Cognitive Dysfunction in Schizophrenia, Affective Disorder and Organic Brain Disease

Published online by Cambridge University Press:  29 January 2018

Richard Abrams ,
Joel Redfield  and
Michael Alan Taylor
Richard Abrams
Affiliation:
Department of Psychiatry and Behavioral Sciences, UHS/The Chicago Medical School, 3333 Green Bay Road, North Chicago, IL 60064
Joel Redfield
Affiliation:
Department of Psychiatry, Beth Israel Medical Center, New York City, N. Y.
Michael Alan Taylor
Affiliation:
Department of Psychiatry and Behavioral Sciences, UHS/The Chicago Medical School
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Summary

We used the Wechsler Adult Itelligence Scale (WAIS) to study a sample of patients with affective disorder (N = 52), schizophrenia (N = 17) and organic brain disease (N = 8). Schizophrenic patients had lower verbal, performance and full-scale IQs than patients with affective disorder, but were no different from those with organic brain disease. An individual WAIS subscale analysis showed that, compared with affectives, schizophrenics had relatively poorer performance on language than non-language tasks.

These differences were independent of age, sex, handedness, educational level or drug administration and are consistent with a variety of studies demonstrating significant cerebral dysfunction in carefully diagnosed schizophrenic patients.

Type
Papers
Information
The British Journal of Psychiatry , Volume 139 , Issue 3 , September 1981 , pp. 190 - 194
Copyright
Copyright © Royal College of Psychiatrists, 1981 

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References

Abrams, R. & Taylor, M. A. (1979) Differential EEG patterns in affective disorder and schizophrenia. Archives of General Psychiatry, 36, 1355–8.Google Scholar
DeWolfe, A. S. (1971) Differentiation of schizophrenia and brain damage with the WAIS. Journal of Clinical Psychology, 27, 209–15.Google Scholar
DeWolfe, A. S., Barrell, R. P., Becker, B. C. & Spaner, F. E. (1971) Intellectual deficit in chronic schizophrenia and brain damage. Journal of Consulting and Clinical Psychology, 36, 197—204.Google Scholar
Flor-Henry, P. (1976) Lateralized temporal-limbic dysfunction and psychopathology. Annals of the New York Academy of Sciences, 280, 777–97.Google Scholar
Goldstein, G. & Halperin, K. M. (1977) Neuropsychological differences among subtypes of schizophrenia. Journal of Abnormal Psychology, 86, 34—40.CrossRefGoogle ScholarPubMed
Heimburger, R. F. & Reitan, R. M. (1961) Easily administered written test for lateralizing brain lesions. Journal of Neurosurgery, 18, 301–12.CrossRefGoogle ScholarPubMed
Johnstone, E. C., Crow, T. J., Frith, C. D., Husband, J. & Kreel, L. (1976) Cerebral ventricular size and cognitive impairment in chronic schizophrenia. Lancet, ii, 924–6.Google Scholar
Johnstone, E. C., Crow, T. J., Frith, C. D., Stevens, M., Kreel, L. & Husband, J. (1978) The dementia of dementia praecox. Acta Psychiatrica Scandinavica, 57, 305–24.Google Scholar
Klonoff, H., Fibiger, C. H. & Hutton, G. H. (1970) Neuropsychological patterns in chronic schizophrenia. Journal of Nervous and Mental Disease, 150, 291—300.Google Scholar
Lacks, P. B., Colbert, J., Harrow, M. & Levine, J. (1970) Further evidence concerning the diagnostic accuracy of the Halstead organic test battery. Journal of Clinical Pscyhology, 26, 480–1.Google Scholar
Smith, A. (1964) Mental deterioration in chronic schizophrenia. Journal of Nervous and Mental Disease, 139, 479–87.Google Scholar
Taylor, M. A., Abrams, R. & Gaztanaga, P. (1975) Manic-depressive illness and schizophrenia: a partial validation of research diagnostic criteria utilizing neuropsychological testing. Comprehensive Psychiatry, 16, 91–6.CrossRefGoogle ScholarPubMed
Taylor, M. A., Greenspan, B. & Abrams, R. (1979) Lateralized neuropsychological dysfunction in affective disorder and schizophrenia. American Journal of. Psychiatry, 136, 1031–4.Google Scholar
Watson, C. G., Thomas, R. W., Andersen, D. & Felling, J. (1968) Differentiation of organics from schizophrenics at two chronicity levels by use of the Reitan-Halstead organic test battery. Journal of Consulting and Clinical Psychology, 32, 679–84.Google Scholar
Watson, C. G. (1965) WAIS profile patterns of hospitalized brain-damaged and schizophrenic patients. Journal of Clinical Psychology, 21, 294–5.Google Scholar
Wechsler, D. (1955) Wechsler Adult Intelligence Scale. N.Y., The Psychological Corporation.Google Scholar
Weinberger, D. R., Torrey, E. F., Neophytides, A. N. & Wyatt, R. J. (1979a) Lateral cerebral ventricular enlargement in chronic schizophrenia. Archives of General Psychiatry, 36, 735–9.Google Scholar
Weinberger, D. R., Torrey, E. F., Neophytides, A. N. & Wyatt, R. J. (1979b) Structural abnormalities in the cerebral cortex of chronic schizophrenic patients. Archives of General Psychiatry, 36, 935–9.Google Scholar
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