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CNS drug discovery in the 21st century

From genomics to combinatorial chemistry and back

Published online by Cambridge University Press:  06 August 2018

Steven Paul*
Affiliation:
CNS Discovery Research and Clinical Investigations, Eli Lilly and Company, Indianapolis, IN, USA

Abstract

The discovery of new drugs for psychiatric and neurological disorders has been greatly facilitated by advances in molecular biology, genetics and chemistry. Several examples are given of how these revolutionary advances have been applied to the discovery of new drugs that selectively modify serotonergic neurotransmission, including compounds which may prove to be more effective antidepressants.

Type
Research Article
Copyright
Copyright © The Royal College of Psychiatrists, 1999 

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