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Body Water Variations in Manic-Depressive Psychosis

Published online by Cambridge University Press:  29 January 2018

R. P. Hullin ,
Angela D. Bailey ,
R. McDonald ,
G. A. Dransfield  and
H. B. Milne
R. P. Hullin
Affiliation:
Biochemistry University of Leeds
Angela D. Bailey
Affiliation:
Biochemistry University of Leeds
R. McDonald
Affiliation:
High Royds Hospital, Menston, Ilkley, Yorkshire
G. A. Dransfield
Affiliation:
High Royds Hospital, Menston, Ilkley, Yorkshire
H. B. Milne
Affiliation:
High Royds Hospital, Menston, Ilkley, Yorkshire
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Extract

Most of the water and electrolyte studies in mental illness have been carried out on patients suffering from periodic disorders and have been reviewed by Crammer (1962). Coppen and Shaw (1963) found increases in total body water and extracellular fluid and a decrease in residual sodium space on recovery from depression. Manic patients with a high vocal productivity were found by Anderson et al. (1964) to have a negative sodium balance, low plasma potassium levels and a positive potassium balance. Depressed patients with a low vocal productivity had a reduced rate of sodium loss and higher plasma potassium levels. Dawson et al. (1956) found extracellular expansion on spontaneous recovery from manic or depressive attacks. The purpose of the present study was to investigate variations in total body water and its distribution in manic-depressive psychosis. The investigation was complementary to a similar study of variations in body composition during recovery from depression reported by Hullin et al. (1967).

Type
Research Article
Information
The British Journal of Psychiatry , Volume 113 , Issue 499 , June 1967 , pp. 584 - 592
Copyright
Copyright © Royal College of Psychiatrists, 1967 

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References

Anderson, W. McC., Dawson, J., and Margerison, J. H. (1964). “Serial biochemical, clinical and electro-encephalographic studies in affective illness.” Clin. Sci., 26, 323–336.Google Scholar
Brown, D. G., Hullin, R. P., and Roberts, J. M. (1963). “Fluid distribution and the response of depression to E.C.T. and imipramine.” Brit. J. Psychiat., 109, 395–398.CrossRefGoogle Scholar
Crammer, J. L. (1959). “Water and sodium in two psychotics.” Lancet, i, 1122–1126.CrossRefGoogle Scholar
Crammer, J. L. (1962). “Electrolytes and mental state.” In: Aspects of Psychiatric Research, p. 401. Ed. by Richter, D., Tanner, J. M., Taylor, and Zangwill, O. L. London: Oxford University Press.Google Scholar
Coppen, A., and Shaw, D. M. (1963). “Mineral metabolism in melancholia.” Brit. med. J., ii, 1439–1444.CrossRefGoogle Scholar
Dawson, J., Hullin, R. P., and Crocket, B. M. (1956). “Metabolic variations in manic-depressive psychosis.” J. ment. Sci., 102, 168–177.CrossRefGoogle Scholar
Hamilton, M. (1960). “A rating scale for depression.” J. Neurol. Neurosurg. Psychiat., 23, 56–62.CrossRefGoogle Scholar
Hullin, R. P., Bailey, A. D., McDonald, R., Dransfield, G. A., and Milne, H. B. (1967). “Variations in body water during recovery from depression.” Brit. J. Psychiat., 113, 573–583.CrossRefGoogle Scholar
Kety, S. S. (1959). “Biochemical theories of schizophrenia.” Science, N.Y., 129, 1528–1532.CrossRefGoogle Scholar
Klein, R., and Nunn, R. F. (1945). “Clinical and biochemical analysis of a case of manic-depressive psychosis showing regular weekly cycles.” J. ment. Sci., 26, 323–336.Google Scholar
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