Hostname: page-component-586b7cd67f-r5fsc Total loading time: 0 Render date: 2024-11-29T18:59:47.257Z Has data issue: false hasContentIssue false
  • English
  • Français

An Icelandic Family Study of Schizophrenia

Published online by Cambridge University Press:  29 January 2018

Jon L. Karlsson
Jon L. Karlsson*
Affiliation:
National Archives, Reykjavik, Iceland
Get access Rights & Permissions [Opens in a new window]

Extract

At the present time there is a renewal of interest in the contribution of biological factors to schizophrenic illness. This stems in part from the success of pharmacological treatment and in part from the impressive findings in studies of foster-reared relatives of schizophrenics. While the pendulum of emphasis thus seems to be generally swinging in favour of constitutional influences, recent reports on twin studies have tended to go in the opposite direction. As will be discussed below, this development is largely attributable to a methodological error in the most recent twin investigations.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 123 , Issue 576 , November 1973 , pp. 549 - 554
Copyright
Copyright © Royal College of Psychiatrists, 1973 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

A synopsis of this paper was published in the May 1973 Journal.

References

Allen, M. G., Cohen, S., and Pollin, W. (1972). ‘Schizophrenia in veteran twins: a diagnostic review.’ American Journal of Psychiatry, 128, 939–945.CrossRefGoogle ScholarPubMed
Book, J. A. (1953). ‘A genetic and neuropsychiatrie investigation of a north-Swedish population.’ Acta Genetica et Statistica Medica, 4, 1–100.Google Scholar
Essen-Möller, E. (1941). ‘Psychiatrische Untersuchungen an einer Serie von Zwillingen.’ Acta Psychiatrica Scandinavica (suppl. 23), 16, 1–100.Google Scholar
Fischer, M., Harvald, B., and Hauge, M. (1969). ‘A Danish twin study of schizophrenia.’ British Journal of Psychiatry, 115, 981–990.CrossRefGoogle ScholarPubMed
Gottesman, I. I., and Shields, J. (1966). ‘Schizophrenia in twins: 16 years' consecutive admissions to a psychiatric clinic’ British Journal of Psychiatry, 112, 809–818.CrossRefGoogle ScholarPubMed
Helgason, T. (1964). ‘Epidemiology of mental disorders in Iceland.’ Acta Psychiatrica Scandinavica (suppl. 173), 40, 1–258.Google ScholarPubMed
Heston, L. L. (1966). ‘Psychiatric disorders in foster home reared children of schizophrenic mothers.’ British Journal of Psychiatry, 112, 819–825.CrossRefGoogle ScholarPubMed
Inouye, E. (1961). ‘Similarity and dissimilarity of schizophrenia in twins.’ Proceedings of Third World Congress of Psychiatry (vol. 1), 524–530.Google Scholar
Kallmann, F. J. (1946). ‘The genetic theory of schizophrenia.’ American Journal of Psychiatry, 103, 309–322.CrossRefGoogle ScholarPubMed
Kallmann, F. J. (1953). Heredity in Health and Mental Disorder. New York.Google Scholar
Karlsson, J. L. (1966). The Biologic Basis of Schizophrenia. Springfield.Google Scholar
Karlsson, J. L. (1970a). ‘A double dominant genetic mechanism for schizophrenia.’ Hereditas, 65, 261–267.CrossRefGoogle ScholarPubMed
Karlsson, J. L. (1970b). ‘The rate of schizophrenia in foster-reared close relatives of schizophrenic index cases.’ Biological Psychiatry, 2, 285–290.Google ScholarPubMed
Karlsson, J. L. (1971). ‘Rates of the schizophrenic genotype in relatives of psychotic persons.’ Hereditas, 69,223–231.CrossRefGoogle ScholarPubMed
Karlsson, J. L. (1972a). ‘Type of dominance modification in schizophrenia.’ Hereditas, 72, 153–158.CrossRefGoogle ScholarPubMed
Karlsson, J. L. (1972b). ‘A two-locus hypothesis for inheritance of schizophrenia’, in Genetic Factors in Schizophrenia (ed. Kaplan, A. R.). Springfield.Google Scholar
Kringlen, E. (1968). ‘An epidemiological-clinical twin study on schizophrenia.’ Journal of Psychiatric Research (Suppl. 1), 6, 49–63.CrossRefGoogle Scholar
Luxenburoer, H. (1928). ‘Vorläufiger Bericht über psychiatrische Serienuntersuchungen an Zwillingen.’ Zeitschrift für die gesamte Neurologie und Psychiatrie, 116, 297–326.CrossRefGoogle Scholar
Pollin, W., Allen, M. G., Hoffer, A., Stabenau, J. R., and Hrubec, Z. (1969). ‘Psychopathology in 15,909 pairs of veterans twins: evidence for a genetic factor in the pathogenesis of schizophrenia and its relative absence in psychoneurosis.’ American Journal of Psychiatry, 126, 597–609.CrossRefGoogle Scholar
Rosanoff, A. J., Handy, L. M., Plesset, I. R., and Brush, S. (1934). ‘The etiology of socalled schizophrenic psychoses.’ American Journal of Psychiatry, 91, 247–286.CrossRefGoogle Scholar
Rosenthal, D., Wender, P. H., Kety, S. S., Schulsinoer, F., Welner, J., and Österoaard, L. (1968). ‘“Schizophrenics” offspring reared in adoptive homes.’ Journal of Psychiatric Research (Suppl. 1), 6, 377–391 CrossRefGoogle Scholar
Slater, E. (1963). ‘Psychotic and neurotic illnesses in twins.’ Medical Research Council Special Report Series No. 287. London.Google Scholar
Slater, E. (1958). ‘The monogenic theory of schizophrenia.’ Acta Genetica et Statistica Medica, 8, 50–56.Google ScholarPubMed
Tienari, P. (1963). ‘Psychiatric illnesses in identical twins.’ Acta Psychiatrica Scandinavica (Suppl. 171), 39, 9–195.Google ScholarPubMed
Zerbin-Rüdin, E. (1972). ‘Genetic research and the theory of schizophrenia.’ International Journal of Mental Health, 1, 42–62.CrossRefGoogle Scholar
Submit a response

eLetters

No eLetters have been published for this article.