Hostname: page-component-586b7cd67f-t7fkt Total loading time: 0 Render date: 2024-11-22T16:44:47.202Z Has data issue: false hasContentIssue false
  • English
  • Français

Amitriptyline in Depressive States: Six-month Treatment Results

Published online by Cambridge University Press:  29 January 2018

Anthony Hordern ,
C. G. Burt ,
W. F. Gordon  and
N. F. Holt
Anthony Hordern
Affiliation:
State Department of Mental Hygiene, Sacramento, California, U.S.A.
C. G. Burt
Affiliation:
Beechworth Hospital, Victoria, Australia
W. F. Gordon
Affiliation:
Royal Park Psychiatric Hospital, Victoria, Australia
N. F. Holt
Affiliation:
Mental Health Research Institute, Victoria, Australia
Get access Rights & Permissions [Opens in a new window]

Extract

The proven effectiveness of electroconvulsive therapy (E.C.T.) and antidepressant drugs has lately led to a resurgence of interest in the treatment of depressive states. Amongst the principal problems currently confronting the clinician, the following would seem to be particularly pertinent: should E.C.T. be used in preference to drugs or vice versa? Which drug is to be preferred? Can drug response be predicted? How long should drugs be given? When are drugs contra-indicated? Given in maintenance dosage after a depressive episode, do antidepressants lower the rate of relapse? This paper, the third report on an investigation of the effectiveness of amitriptyline (‘Tryptizol’, ‘Elavil’, ‘Tryptanol’) and imipramine (‘Tofranil’) in depressive states, sets out to answer the above questions in the light of the results that were obtained.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 110 , Issue 468 , September 1964 , pp. 641 - 647
Copyright
Copyright © Royal College of Psychiatrists, 1964 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Ayd, F. J. Jr. (1960). “Amitriptyline therapy for depressive reactions.” Psychosomatics, 1, 1–6.CrossRefGoogle Scholar
Ayd, F. J. (1961). “A critique of antidepressants.” Dis. Nerv. Syst., 22, 32–36, supp. Google Scholar
Burt, C. C., Gordon, W. F., Holt, N. F., and Hordern, A. (1962). “Amitriptyline in depressive states: a controlled trial.” J. Ment. Sci., 108, 711–730.CrossRefGoogle Scholar
Cole, J. O., Jones, R. T., and Klerman, G. L. (1961). “Drug therapy”, in Progress in Neurology and Psychiatry. Volume XVI (ed. Spiegel, E. A.). New York: Grune and Stratton. pp. 539–574.Google Scholar
Denser, H. C. B., Rajotte, P., and Ross, E. (1960). “Some observations on the chemotherapy of depression: results with ‘Taractan’.” Comprehen. Psychiat., 1, 308–312.Google Scholar
Hamilton, M. (1960). “A rating scale for depression.” J. Neurol. Neurosurg. Psychiat., 23, 56–62.CrossRefGoogle Scholar
Hordern, A., Holt, N. F., Burt, C. C., and Gordon, W. F. (1963). “Amitriptyline in depressive states: phenomonology and prognostic considerations.” Brit. J. Psychiat., 109, 815–825.CrossRefGoogle Scholar
Karaoulla, S. (1950). “Evaluation of electro-convulsive therapy as compared with conservative methods of treatment in depressive states.” J. Merit. Sci., 96, 1060–1091.Google Scholar
Kiloh, L. G. Child, J. P., and Latner, G. (1960). “Endogenous depression treated with iproniazid—a follow-up study.” Ibid., 106, 1425–1428.Google Scholar
Kiloh, and Ball, J. R. B. (1961). “Depression treated with imipramine—a follow-up study.” Brit. Med. J., i, 168–171.CrossRefGoogle Scholar
Thomas, D. L. L. (1954). “Prognosis of depression with electrical treatment.” Ibid., ii, 950–954.Google Scholar
Tooth, G. C., and Newton, M. P. (1961). Leucotomy in England and Wales, 1952–1954. London: Her Majesty's Stationery Office.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.