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Acute Toxic Psychosis in Two Children Treated with Benzhexol Hydrochloride (Artane)

Published online by Cambridge University Press:  29 January 2018

Dora Black  and
Susan Woollacott
Dora Black
Affiliation:
Hospital for Sick Children, Great Ormond Street, London, WC1N 3JH; Edgware General Hospital, Edgware, Middlesex
Susan Woollacott
Affiliation:
Department of Psychological Medicine, Hospital for Sick Children, Great Ormond Street, London WC1N 3JH
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Extract

Although there have been reports of psychotic reactions to benzhexol hydrochloride in adults we have not found any reports of adverse reactions in children. Recently, at the in-patient psychiatric unit of the Hospital for Sick Children, Great Ormond Street, London, we have seen two children who developed acute psychotic reactions when treated with benzhexol hydrochloride given to prevent extra-pyramidal side effects. In both cases, complete recovery occurred rapidly when benzhexol was discontinued.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 125 , Issue 588 , November 1974 , pp. 483 - 484
Copyright
Copyright © Royal College of Psychiatrists, 1974 

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References

Ananth, J. V. Lehmann, H. E. & Ban, T. A. (1970) Toxic psychosis induced by benzhexol hydrochloride. Canadian Medical Association Journal, 10 October, p. 103.Google Scholar
Bachrich, P. M. (1964) New drugs of addiction. British Medical Journal, i, 834.Google Scholar
Stephens, D. A. (1967) Psychotic effects of benzhexol hydrochloride (Artane). British Journal of Psychiatry, 113, 1213–18.Google Scholar
Warnes, H. (1967) Toxic psychosis due to antiparkinsonian drugs. Canadian Psychiatric Association Journal, 12, 23.Google Scholar
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