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The Dual Life of RNA

Published online by Cambridge University Press:  19 September 2017

M. Meli  and
M-C. Maurel
M. Meli
Affiliation:
Evolutionary Biochemistry and Molecular Adaptation, Jacques-Monod Institute, University Paris VI, Tour 43, 2 place Jussieu, 75251 Paris, France (E-mail: [email protected])
M-C. Maurel
Affiliation:
Evolutionary Biochemistry and Molecular Adaptation, Jacques-Monod Institute, University Paris VI, Tour 43, 2 place Jussieu, 75251 Paris, France (E-mail: [email protected])

Abstract

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Molecular biology techniques have enabled us to prepare and select RNA aptamers that can bind specifically to small targets. RNA oligonucleotides can also be used as fluorescent probes. We have combined the two approaches to obtain Aptamer Beacons, in which molecular recognition is linked to the emission of an optical signal. These RNA biosensors could be used to detect directly the signatures of life in samples of mineral and extra-terrestrial material.

Type
Origins and Evolution of Life
Information
Symposium - International Astronomical Union , Volume 213: Bioastronomy 2002: Life Among the stars , 2004 , pp. 315 - 320
Copyright
Copyright © Astronomical Society of the Pacific 2004 

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