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Disorders of the lower gastrointestinal tract

Published online by Cambridge University Press:  17 November 2008

JA Barrett  and
D Chew
JA Barrett*
Affiliation:
Clatterbridge Hospital, Wirral, Merseyside
D Chew
Affiliation:
Walton Hospital, Chesterfield, Derbyshire
*
JA Barrett, Consultant Physician in Geriatric Medicine and Rehabilitation, Clatterbridge Hospital, Wirral, Merseyside, UK.
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Abstract

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Type
Clinical geriatrics
Information
Reviews in Clinical Gerontology , Volume 1 , Issue 2 , May 1991 , pp. 119 - 134
Copyright
Copyright © Cambridge University Press 1991

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References

1Wolf, EL, Frager, D, Beneventano, T. Feasibility of double contrast barium enema in the elderly. AJR 1986; 145: 47–48.CrossRefGoogle Scholar
2Irvine, EJ, O'Connor, J, Frost, RA et al. Prospective comparison of double contrast barium enema plus flexible sigmoidoscopy v colonoscopy in rectal bleeding: barium enema v colonoscopy in rectal bleeding. Gut 1988; 29: 1188–93.Google Scholar
3Rex, DK, Weddle, RA, Lehman, GA et al. Flexible sigmoidoscopy plus air contrast barium enema versus colonoscopy for suspected lower gastrointestinal bleeding. Gastroenterology 1990; 98: 855–61.Google Scholar
4Fielding, LP, Phillips, RKS, Hittinger, R. Factors influencing mortality after curative surgery for large bowel cancer in elderly patients. Lancet 1989; i: 595–97.Google Scholar
5Seymour, DG, Vaz, FG. Aspects of surgery in the elderly: preoperative medical assessment. Br J Hosp Med 1987; 37: 431–35.Google Scholar
6Barr, H, Brown, SG, Krasner, N, Boulos, PB. Photodynamic therapy for colorectal disease. Int J Colorectal Dis 1989; 4: 15–19.Google Scholar
7Krasner, N. Laser therapy in the management of benign and malignant tumours in the colon and rectum. Int J Colorectal Dis 1989; 4: 2–5.CrossRefGoogle ScholarPubMed
8Lewis, AAM, Khoury, GA. Resection for colorectal cancer in the very old: are the risks too high? Br Med J 1988; 296: 459–61.Google Scholar
9Thomas, WM, Pye, G, Hardcastle, JD, Mangham, CM. Faecal occult blood screening for colorectal neoplasia: a randomised trial of three days of six days of tests. Br J Surg 1990; 77: 277–79.Google Scholar
10Jewell, DP. Aetiology and pathogenesis of ulcerative colitis and Crohn's disease. Postgrad Med J 1989; 65: 718–19.Google Scholar
11Morris, T, Rhodes, J. Incidence of ulcerative colitis in the Cardiff region 1968–1977. Gut 1984; 25: 846–48.Google Scholar
12Zimmerman, J, Gavish, D, Rachmilewitz, D. Early and late onset ulcerative colitis. Distinct clinical features. J Clin Gastroenterol 1985; 7: 492–98.Google Scholar
13Gupta, S, Saverymuttu, SH, Keshavarzian, A, Hodgson, HJF. Is the pattern of inflammatory bowel disease different in the elderly? Age Ageing 1985; 14: 366–70.CrossRefGoogle ScholarPubMed
14Mendeloff, AI, Calkins, BM. The epidemiology of idiopathic inflammatory bowel disease. In: Kirsner, JB, Shorter, RG eds. Inflammatory bowel disease. Philadelphia: Lea & Febiger, 1988: 3–34.Google Scholar
15Jones, HW, Hoare, AM. Does ulcerative colitis behave differently in the elderly? Age Ageing 1988; 17: 410–14.Google Scholar
16Hawkey, CJ, Hawthorne, AB. Medical treatment of ulcerative colitis: scoring the advances. Gut 1988; 29: 1298–303.Google Scholar
17Riley, SA, Mani, V, Goodman, MJ, Herd, ME, Dutt, S, Turnberg, LA. Comparison of delayed release 5-aminosalicylic acid (mesalazine) and sulfasalazine in the treatment of mild to moderate ulcerative colitis relapse. Gut 1988; 29: 669–74.CrossRefGoogle ScholarPubMed
18Riley, SA, Mani, V, Goodman, MJ, Herd, ME, Dutt, S, Turnberg, LA. Comparison of delayed release 5-aminosalicylic acid (mesalazine) and sulfasalazine as maintenance treatment for patients with ulcerative colitis. Gastroenterology 1988; 94: 1383–89.CrossRefGoogle ScholarPubMed
19Meyers, S, Sacher, DB, Present, DH, Janowitz, B. Olsalazine sodium in the treatment of ulcerative colitis among patients intolerant of sulpfasalazine. A prospective, randomised, placebo controlled, double blind, dose ranging trial. Gastroenterology 1987; 93: 1255–62.Google Scholar
20Ritchie, JK, Ritchie, SM, McIntyre, PB, Marks, CG. Management of acute severe ulcerative colitis in district hospitals. J R Soc Med 1984; 77: 465–71.CrossRefGoogle ScholarPubMed
21Kumar, D, Williams, NS. Surgical management of ulcerative colitis. Hospital Update 1990; 16:113–20.Google Scholar
22Rose, JDR, Roberts, GM, Williams, G, Mayberry, JF, Rhodes, J. Cardiff Crohn's disease jubilee: the incidence over 50 years. Gut 1988; 29: 346–51.CrossRefGoogle ScholarPubMed
23Shapiro, PA, Peppercorn, MA, Antonioli, DA, Joffe, N, Goldman, H. Crohn's disease in the elderly. Am J Gastroenterol 1981; 76: 132–37.Google Scholar
24Fabricus, PJ, Gyde, SN, Shouler, P, Keighley, MRB, Alexander-Williams, J, Allan, RN. Crohn's disease in the elderly. Gut 1985; 26: 461–65.CrossRefGoogle Scholar
25Harper, PC, McAuliffe, TL, Beekon, WL. Crohn's disease in the elderly: a statistical comparison with younger patients matched for sex and duration of disease. Arch Intern Med 1986; 146: 753–55.CrossRefGoogle ScholarPubMed
26Brandt, LJ, Boley, SJ, Goldberg, L, Mitsudo, S, Berman, A. Colitis in the elderly: a reappraisal. Am J Gastroenterol 1981; 76: 239–45.Google Scholar
27Ursing, B, Aim, T, Barany, F et al. A comparative study of metranidazole and sulfasalazine for active Crohn's disease. The cooperative Crohn's disease study in Sweden. II: Results. Gastroenterology 1982; 83: 550–62.CrossRefGoogle Scholar
28Prior, P, Gyde, S, Cooke, WT, Waterhouse, JAH, Allan, RN. Mortality in Crohn's disease. Gastroenterology 1981; 80: 307–12.CrossRefGoogle ScholarPubMed
29Elliott, PR, Ritchie, JK, Lennard-Jones, JE. Prognosis of colonie Crohn's disease. Br Med J 1985; 291:178.CrossRefGoogle Scholar
30Gyde, SN, Prior, P, Allan, RN et al. Colorectal cancer in ulcerative colitis: a cohort study of primary referrals from three centres. Gut 1988; 29: 206–17.Google Scholar
31Jones, HW, Grogono, J, Hoare, AM. Surveillance in ulcerative colitis: burdens and benefits. Gut 1988; 29: 325–31.CrossRefGoogle Scholar
32Greenstein, AJ, Meyers, S, Szporn, A, Slater, G, Janowitz, HD, Antses, AH. Colorectal cancer in regional ileitis. Q J Med 1987; 62: 33–40.Google Scholar
33Sharp, JCM. Salmonellosis and eggs. Br Med J 1988; 297: 1557–58.Google Scholar
34Cowden, JM, Lynch, D, Joseph, C A et al. Case-control study of infections with Salmonella enteritidis phage type 4 in England. Br Med J 1989; 299: 771–73.Google Scholar
35Anders, BJ, Lauer, BA, Paisley, JW, Relier, LB. Double blind placebo controlled trial of erythromycin in the treatment of Campylobacter enteritis. Lancet 1982; i: 131–32.CrossRefGoogle Scholar
36Read, NW, Haynes, WG, Bartolo, DCC et al. Use of anorectal manometry during rectal infusion of saline to investigate sphincter function in incontinent patients. Gastroenterology 1983; 85: 105–13.Google Scholar
37Frenckner, B, Euler, CV. Influence of pudendal nerve block on the function of the anal sphincter in man. Gut 1975; 16: 482–89.Google Scholar
38Rogers, J, Henry, MM, Misiewicz, JJ. Combined sensory and motor deficit in primary neuropathic faecal incontinence. Gut 1988; 29: 5–9.Google Scholar
39Gibbons, CP, Trowbridge, EA, Bannister, JJ, Read, NW. Role of anal cushions in maintaining continence. Lancet 1986; i: 886–88.Google Scholar
40Smith, B. Effect of irritant purgatives on the myenteric plexus in man and the mouse. Gut 1968; 9: 139–43.Google Scholar
41Donald, IP, Smith, RG, Cruikshank, JG, Elton, RA, Stoddart, ME. A study of constipation in the elderly living at home. Gerontology 1985; 31: 112–18.Google Scholar
42Barrett, JA. Effect of wheat bran on stool size. Br Med J 1988; 296: 1127–28.Google Scholar
43Smith, RG, Lewis, S. The relationship between digital rectal examination and abdominal radiographs in elderly patients. Age Ageing 1990; 19: 142–43.CrossRefGoogle ScholarPubMed
44Barrett, JA, Faragher, EB, Kiff, ES, Ferguson, G, Brocklehurst, JC. Why are geriatric patients incontinent of faeces? Clin Sci 1988; 75 (suppl 19): 10P.CrossRefGoogle Scholar
45Barrett, JA. A study of the pathophysiology of faecal incontinence among geriatric patients [Thesis]. Liverpool: University of Liverpool, 1988.Google Scholar
46Bassotti, G, Gaburri, M, Imbimbo, B, Pelli, MA, Morelli, A. Colonic mass movements in health and in constipation. Gastroenterology 1987; 92: 1310.Google Scholar
47Roe, AM, Bartolo, DCC, Mortensen, NJMcC. Diagnosis and surgical management of intractable constipation. Br J Surg 1986; 73: 854–61.Google Scholar
48Hinton, JM, Lennard-Jones, Young AC. A new method for studying gut transit times using radioopaque markers. Gut 1969; 10: 842–47.Google Scholar
49Cummings, JH, Jenkins, DJA, Wiggins, HS. Measurement of the mean transit time of dietary residue through the human gut. Gut 1976; 17: 210–18.Google Scholar
50Burkitt, DP, Walker, ARP, Painter, NS. Effect of dietary fibre on stools and transit-times, and its role in the causation of disease. Lancet 1972; ii: 1408–11.Google Scholar
51Brocklehurst, JC, Kirkland, JL, Martin, J, Ashford, J. Constipation in long-stay elderly patients: its treatment and prevention by lactulose, poloxalkol-dihydroxyanthroquinolone and phosphate enemas. Gerontology 1983; 29: 181–84.Google Scholar
52Preston, DM. Arbuthnot Lane's disease; chronic intestinal stasis. Br J Surg 1985; 72 (suppl): S8–10.Google Scholar
53Preston, DM, Lennard-Jones, JE. Anismus in chronic constipation. Digestive Dis Sci 1985; 30: 413–18.CrossRefGoogle ScholarPubMed
54Preston, DM, Butler, MG, Smith, B, Lennard-Jones, JE. Neuropathology of slow transit constipation. Gut 1983; 24: A997.Google Scholar
55Krishnamurphy, S, Schniffer, MD, Rohrmann, CA, Ope, CE. Severe idiopathic constipation is associated with a distinctive abnormality of the colonic myenteric plexus. Gastroenterology 1985; 88: 26–34.Google Scholar
56Preston, DM, Lennard-Jones, JE. Pelvic colon motility and response to intraluminal bisacodyl in slow transit constipation. Digestive Dis Sci 1985; 30: 289–94.CrossRefGoogle ScholarPubMed
57Devroede, G, Lamarche, J. Functional importance of extrinsic parasympathetic innervation of the distal colon and rectum in man. Gastroenterology 1974; 66: 273–80.Google Scholar
58Devroede, G, Arhan, P, Duguay, C, Tetreault, L, Akanry, M, Percy, B. Traumatic constipation. Gastroenterology 1979; 77: 1258–67.CrossRefGoogle ScholarPubMed
59Youle, MS, Read, NW. Effect of painless rectal distension on gastrointestinal transit of solid meal. Digestive Dis Sci 1984; 29: 902–906.CrossRefGoogle ScholarPubMed
60Kellow, JE, Gill, RC, Wingate, DL. Modulation of human upper gastrointestinal motility by rectal distension. Gut 1987; 28: 864–68.Google Scholar
61Bannister, JJ, Timms, JM, Barfield, LJ, Donnelly, TC, Read, NW. Physiological studies in young women with chronic constipation. Int J Colorectal Dis 1986; 1: 175–82.CrossRefGoogle ScholarPubMed
62Barnes, PRH, Lennard-Jones, JE. Balloon expulsion from the rectum in constipation of different types. Gut 1985; 26: 1049–52.CrossRefGoogle ScholarPubMed
63Read, NW, Timms, JM, Barfield, LJ, Donnelly, TC, Bannister, JJ. Impairment of defaecation in young women with severe constipation. Gastroenterology 1986; 90: 53–60.CrossRefGoogle ScholarPubMed
64Turnbull, GK, Lennard-Jones, JE, Bartram, CI. Failure of rectal expulsion as a cause of constipation: why fibre and laxatives sometimes fail. Lancet 1986; i: 767–69.Google Scholar
65Preston, DM, Lennard-Jones, JE, Thomas, BM. The balloon proctogram. Br J Surg 1984; 71: 29–32.CrossRefGoogle ScholarPubMed
66Bartolo, DCC, Read, NW, Jarratt, JA, Read, MG, Donnelly, TC, Johnson, AG. Differences in anal sphincter function and clinical presentation in patients with pelvic floor descent. Gastroenterology 1983; 85: 68–75.Google Scholar
67Womack, NR, Williams, NS, Holmfield, JHM, Morrison, JFB, Simpkins, KC. New method for the dynamic assessment of anorectal function in constipation. Br J Surg 1985; 72: 994–98.Google Scholar
68Kuipers, HC, Bleijeuberg, G, Morree, HDE. The spastic pelvic floor syndrome. Large bowel outlet obstruction caused by pelvic floor dysfunction: a radiological study. Int J Colorectal Dis 1986; 1: 44–48.CrossRefGoogle Scholar
69Lawson, JN, Nixon, HH. Anal canal pressures in the diagnosis of Hirschsprung's disease. J Paediatr Surg 1967; 2: 544–52.CrossRefGoogle ScholarPubMed
70Read, NW, Abouzekry, L. Why do patients with faecal impaction have faecal incontinence? Gut 1986; 27: 283–87.CrossRefGoogle ScholarPubMed
71Bartolo, DCC, Roe, AM, Virjee, J, Mortensen, NJMcC. Evacuation proctography in obstructed defaecation and rectal intussusception. Br J Surg 1985; 72 (suppl): S111–16.CrossRefGoogle ScholarPubMed
72Womack, NR, Morrison, JFB, Williams, NS. The role of pelvic floor denervation in the aetiology of idiopathic faecal incontinence. Br J Surg 1986; 73: 404–407.CrossRefGoogle ScholarPubMed
73Bannister, JJ, Davison, P, Timms, JM, Gibbons, C, Read, NW. Effect of stool size and consistency on defaecation. Gut 1987; 28: 1246–50.Google Scholar
74Read, NW, Abouzekry, L, Read, MG, Howell, P, Ottewell, D, Donnelly, TC. Anorectal function in elderly patients with faecal impaction. Gastroenterology 1985; 89: 959–66.CrossRefGoogle Scholar
75Bannister, JJ, Abouzekry, L, Read, NW. Effect of aging on anorectal function. Gut 1987; 28: 353–57.CrossRefGoogle ScholarPubMed
76Varma, JS, Bradnock, J, Smith, RG, Smith, AN. Constipation in the elderly. A physiologic study. Dis Colon Rectum 1988; 31: 111–15.Google Scholar
77Thomas, TM, Egan, M, Meade, TW. Prevalence and implications of faecal (and double) incontinence. Br J Surg 1985; 72 (suppl): S141.Google Scholar
78Tobin, GW, Brocklehurst, JC. Faecal incontinence in residential homes for the elderly: prevalence, aetiology and management. Age Ageing 1986; 15: 41–46.Google Scholar
79Capewell, AE, Primrose, WR, MacIntyre, C. Nursing dependency in registered nursing homes and long term care geriatric wards in Edinburgh. Br Med J 1986; 292: 1719–21.Google Scholar
80Snooks, SJ, Henry, MM, Swash, M. Anorectal incontinence and rectal prolapse: differential assessment of the innervation to puborectalis and external anal sphincter muscles. Gut 1985; 26: 470–76.CrossRefGoogle ScholarPubMed
81Read, NW, Harford, WV, Schmulen, AC, Read, MG, Santa, Ana CA, Fordtran, JS. A clinical study of patients with faecal incontinence and diarrhoea. Gastroenterology 1979; 76: 747–56.Google Scholar
82Kiff, ES, Swash, M. Slowed conduction in the pudendal nerves in idiopathic (neurogenic) faecal incontinence. Br J Surg 1984; 71: 614–16.Google Scholar
83Parks, AG, Swash, M, Urich, H. Sphincter denervation in anorectal incontinence and rectal prolapse. Gut 1977; 18: 656–65.Google Scholar
84Beersiek, F, Parks, AG, Swash, M. Pathogenesis of anorectal incontinence. A histometric study of the anal sphincter musculature. J Neural Sci 1979; 42: 111–27.CrossRefGoogle ScholarPubMed
85Neill, ME, Parks, AG, Swash, M. Physiological studies of the anal sphincter musculature in faecal incontinence and rectal prolapse. Br J Surg 1981; 68: 531–36.Google Scholar
86Kiff, ES, Swash, M. Normal proximal and delayed distal conduction in the pudendal nerves of patients with idiopathic (neurogenic) faecal incontinence. J Neural Neurosurg Psychiatry 1984; 47: 820–23.CrossRefGoogle ScholarPubMed
87Bartolo, DCC, Jarratt, JA, Read, NW. The use of conventional electromyography to assess external sphincter neuropathy in man. J Neural Neurosurg Psychiatry 1983; 46: 1115–18.Google Scholar
88Bartolo, DCC, Jarratt, JA, Read, MG, Donnelly, TC, Read, NW. The role of partial denervation of the puborectalis muscle in idiopathic faecal incontinence. Br J Surg 1983; 70: 664–67.CrossRefGoogle ScholarPubMed
89Kiff, ES, Barnes, PRH, Swash, M. Evidence of pudendal neuropathy in patients with perineal descent and chronic straining at stool. Gut 1984; 25: 1279–82.Google Scholar
90Snooks, SJ, Barnes, PRH, Swash, M, Henry, MM. Damage to the innervation of the pelvic floor musculature in chronic constipation. Gastroenterology 1985; 89: 977–81.CrossRefGoogle Scholar
91Snooks, SJ, Henry, MM, Swash, M. Faecal incontinence due to external anal sphincter division in childbirth is associated with damage to the innervation of the pelvic floor musculature: a double pathology. Br J Obstet Gynaecol 1985; 92: 824–28.CrossRefGoogle Scholar
92Snooks, SJ, Setchell, M, Swash, M, Henry, MM. Injury to the innervation of the pelvic floor musculature in childbirth. Lancet 1984; ii: 546–50.CrossRefGoogle Scholar
93Read, NW, Bartolo, DCC, Read, MG. Differences in anal function in patients with incontinence to solids and in patients with incontinence to liquids. Br J Surg 1984; 71: 39–42.CrossRefGoogle ScholarPubMed
94Matheson, DM, Keighley, MRB. Manometric evaluation of rectal prolapse and faecal incontinence. Gut 1981; 22: 126–29.Google Scholar
95Laurberg, S, Swash, M. Effects of ageing on the anorectal sphincters and their innervation. Dis Colon Rectum 1989; 32: 737–42.Google Scholar
96Percy, JP, Neill, ME, Kandiah, TK, Swash, M. A neurogenic factor in faecal incontinence in the elderly. Age Ageing 1982; 11: 175–79.Google Scholar
97Neill, ME, Swash, M. Increased motor unit fibre density in the external anal sphincter in ano-rectal incontinence: a single fibre EMG study. J Neural Neurosurg Psychiatry 1980; 43: 343–47.CrossRefGoogle ScholarPubMed
98Grimby, G, Saltin, B. Mini-review. The ageing muscle. Clin Physiol 1983; 3: 209–18.Google Scholar
99Barrett, JA, Brocklehurst, JC, Kiff, ES, Ferguson, G. Anal function in geriatric patients with faecal incontinence. Gut 1989; 30: 1244–51.Google Scholar
100Frenckner, B. Function of the anal sphincters in spinal man. Gut 1975; 16: 638–44.Google Scholar
101Wheatley, IC, Hardy, KJ, Dent, J. Anal pressure studies in spinal patients. Gut 1977; 18: 488–90.Google Scholar
102McHugh, SM, Diamant, NE. Effect of age, gender, and parity on anal canal pressures. Digestive Dis Sci 1987; 32: 726–36.Google Scholar
103Loening-Baucke, V, Anuras, S. Anorectal manometry in healthy elderly subjects. J Am Geriatr Soc 1984; 32: 636–39.Google Scholar
104Tobin, GW. Incontinence in the elderly. Practitioner 1987; 231: 843–47.Google Scholar
105Roe, AM, Bartolo, DCC, Mortensen, NJMcC. New method for assessment of anal sensation in various anorectal disorders. Br J Surg 1986; 73: 310–12.CrossRefGoogle ScholarPubMed
106Miller, R, Bartolo, DCC, Cervero, F, Mortensen, NJMcC. Anorectal temperature sensation: a comparison of normal and incontinent patients. Br J Surg 1987; 74: 511–15.Google Scholar
107Read, MG, Read, NW. Role of anorectal sensation in preserving continence. Gut 1982; 23: 345–47.Google Scholar
108Barrett, JA, Brocklehurst, JC, Kiff, ES, Ferguson, G, Faragher, EB. Rectal motility studies in geriatric patients with faecal incontinence. Age Ageing 1990; 19: 311–17.CrossRefGoogle Scholar
109Buser, WD, Miner, PB. Delayed rectal sensation with faecal incontinence. Successful treatment using anorectal manometry. Gastroenterology 1986; 91: 1186–91.CrossRefGoogle ScholarPubMed
110Wald, A, Tunuguntla, AK. Anorectal sensorimotor dysfunction in faecal incontinence and diabetes mellitus. Modification with biofeedback therapy. N Engl J Med 1984; 310: 1282–87.Google Scholar
111Ferguson, GH, Redford, J, Barrett, JA, Kiff, ES. The appreciation of rectal distension in faecal incontinence. Dis Colon Rectum 1989; 32: 964–67.Google Scholar
112Brocklehurst, JC, Andrews, K, Richards, B, Laycock, PJ. Incidence and correlates of incontinence in stroke patients. J Am Geriatr Soc 1985; 33: 540–42.Google Scholar
113Ardron, ME, Main, ANH. Management of constipation. Br Med J 1990; 300: 1400.CrossRefGoogle ScholarPubMed
114Goodman, J, Pang, J, Bessman, AN. Dioctyl sodium sulphasuccinate – an ineffective prophylactic laxative. J Chronic Dis 1976; 29: 59–63.Google Scholar
115Smith, RG, Currie, JEJ, Walls, ADF. Whole gut irrigation: a new treatment for constipation. Br Med J 1978; 2: 396–97.Google Scholar
116Puxty, JAH, Fox, RA. Golytely: a new approach to faecal impaction in old age. Age Ageing 1986; 15: 182–84.Google Scholar
117Foord, KD, Morcos, SK, Ward, P. A comparison of mannitol and magnesium citrate preparations for double-contrast barium enema. Clin Radiol 1983; 34: 309–12.Google Scholar
118Schiller, LR, Santa, Ana CA, Morawski, SG, Fordtran, JS. Mechanism of the anti diarrheal effect of loperamide. Gastroenterology 1984; 86: 1475–80.Google Scholar
119Kachel, G, Ruppin, H, Hagel, J, Barina, W, Meinhardt, M, Domschke, W. Human intestinal motor activity and transport: effects of a synthetic opiate. Gastroenterology 1986; 90: 85–93.Google Scholar
120Rattan, S, Culver, PJ. Influence of loperamide on the internal anal sphincter in the oppossum. Gastroenterology 1987; 93: 121–28.Google Scholar
121Read, M, Read, NW, Barber, DC, Duthie, HL. Effects of loperamide on anal sphincter function in patients complaining of chronic diarrhoea with faecal incontinence and urgency. Digestive Dis Sci 1982; 27: 807–14.Google Scholar
122Parks, AG. Post-anal perineorrhaphy for rectal prolapse. Proc R Soc Med 1967; 60: 920–21.Google ScholarPubMed
123Henry, MM, Simson, JNL. Results of postanal repair: a retrospective study. Br J Surg 1985; 72 (suppl): S17–19.Google Scholar