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Perturbed angular correlation spectroscopy and its application to metal sites in proteins: possibilities and limitations

Published online by Cambridge University Press:  17 March 2009

Rogert Bauer
Rogert Bauer
Affiliation:
Department of Physics, The Royal Veterinary and Agricultural University, DK-1871, Copenhagen V, Denmark
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Extract

The present review describes the methodology of perturbed angular correlation of gamma rays (PAC) applied to biological problems. A large part of the present review focuses on the application of PAC spectroscopy to the study of coordination geometry for the metal site in zinc enzymes. Applications to conformation and dynamics of biomolecules and the use of the method to identify the intracellular sites of either metals or labelled proteins are also discussed.

Type
Research Article
Information
Quarterly Reviews of Biophysics , Volume 18 , Issue 1 , February 1985 , pp. 1 - 64
Copyright
Copyright © Cambridge University Press 1985

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References

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