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Interrelations of bioenergetic and sensory functions of the retinal proteins

Published online by Cambridge University Press:  17 March 2009

Vladimir P. Skulachev
Vladimir P. Skulachev
Affiliation:
Department of Bioenergetics, A. N. Belozersky Institute of Physico-Chemical Biology, Moscow State University, Moscow 119899, Russia
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Extract

Rhodopsins are intrinsic membrane retinal-containing proteins composed of 7 hydrophobic a-helical transmembrane columns and hydrophilic sequences of various length connecting the helices and localized at N- and C-ends of the polypeptide. The chromophore (retinal) forms a Schiff base with a lysine residue in the middle part of the last a-helix. Absorption of a photon results in isomerization of retinal which gives rise to a conformational change in the protein moiety.

Type
Research Article
Information
Quarterly Reviews of Biophysics , Volume 26 , Issue 2 , May 1993 , pp. 177 - 199
Copyright
Copyright © Cambridge University Press 1993

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References

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