A model is presented for item responses when different subjects employ different strategies, but only responses, not choice of strategy, can be observed. Using substantive theory to differentiate the likelihoods of response vectors under a fixed set of strategies, we model response probabilities in terms of item parameters for each strategy, proportions of subjects employing each strategy, and distributions of subject proficiency within strategies. The probabilities that an individual subject employed the various strategies can then be obtained, along with a conditional estimate of proficiency under each. A conceptual example discusses response strategies for spatial rotation tasks, and a numerican example resolves a population of subjects into subpopulations of valid responders and random guessers.