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Short- and long-term memory in patients with presenile dementia (Alzheimer's disease)

Published online by Cambridge University Press:  09 July 2009

Edgar Miller
Edgar Miller
Affiliation:
From the Department of Psychiatry, University of Southampton
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Synopsis

Evidence is presented to show that patients with Alzheimer's disease owe their memory disturbance to both an impairment in short-term memory and an additional difficulty in establishing new material in long-term storage. These findings are particularly discussed in relation to the notion that, since the pathological changes in Alzheimer's disease are particularly manifest in the hippocampal region, then this involvement of the hippocampus might explain the memory disorder. The present experiment, which is similar to one previously reported using subjects with bilateral hippocampal lesions, shows the two types of memory disorder resulting from bilateral hippocampal damage and Alzheimer's disease to be qualitatively different. Some outstanding problems with regard to obtaining a complete understanding of the nature of the amnesic phenomena in Alzheimer's disease are discussed.

Type
Research Article
Information
Psychological Medicine , Volume 3 , Issue 2 , May 1973 , pp. 221 - 224
Copyright
Copyright © Cambridge University Press 1973

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References

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