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Reduced total complement haemolytic activity in schizophrenic patients

Published online by Cambridge University Press:  09 July 2009

Baruch Spivak ,
Marguerite Radwan ,
Jonathan Brandon ,
Yehuda Baruch ,
Mike Stawski ,
Sam Tyano  and
Abraham Weizman
Baruch Spivak*
Affiliation:
Geha Psychiatric Hospital, Beilinson Medical Center, Petah Tiqva, Sackler Faculty of Medicine, Tel Aviv University, Israel
Marguerite Radwan
Affiliation:
Geha Psychiatric Hospital, Beilinson Medical Center, Petah Tiqva, Sackler Faculty of Medicine, Tel Aviv University, Israel
Jonathan Brandon
Affiliation:
Geha Psychiatric Hospital, Beilinson Medical Center, Petah Tiqva, Sackler Faculty of Medicine, Tel Aviv University, Israel
Yehuda Baruch
Affiliation:
Geha Psychiatric Hospital, Beilinson Medical Center, Petah Tiqva, Sackler Faculty of Medicine, Tel Aviv University, Israel
Mike Stawski
Affiliation:
Geha Psychiatric Hospital, Beilinson Medical Center, Petah Tiqva, Sackler Faculty of Medicine, Tel Aviv University, Israel
Sam Tyano
Affiliation:
Geha Psychiatric Hospital, Beilinson Medical Center, Petah Tiqva, Sackler Faculty of Medicine, Tel Aviv University, Israel
Abraham Weizman
Affiliation:
Geha Psychiatric Hospital, Beilinson Medical Center, Petah Tiqva, Sackler Faculty of Medicine, Tel Aviv University, Israel
*
1Address for correspondence: Dr B. Spivak, Geha Psychiatric Hospital, Beilinson Medical Center, PO Box 102, Petah Tiqva 49100, Israel.
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Synopsis

Serum concentrations of the third and fourth components of the complement system and total complement haemolytic activity were measured in 167 psychiatric patients. Total complement haemolytic activity was decreased in chronic schizophrenic patients as compared to healthy controls and bipolar patients. The relatively diminished total haemolytic activity was not attributable to drug treatment. It is not clear if the reduced total haemolytic activity is an epiphenomenon or related to the involvement of an autoimmune process in the pathophysiology of schizophrenia.

Type
Original Articles
Information
Psychological Medicine , Volume 23 , Issue 2 , May 1993 , pp. 315 - 318
Copyright
Copyright © Cambridge University Press 1993

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