Hostname: page-component-cd9895bd7-mkpzs Total loading time: 0 Render date: 2024-12-23T00:43:44.689Z Has data issue: false hasContentIssue false

Psychosis after acute alteration of thyroid status

Published online by Cambridge University Press:  09 July 2009

P. D. Bewsher
Affiliation:
University of Aberdeen and Royal Cornfield Hospital, Aberdeen
A. Q. Gardiner
Affiliation:
University of Aberdeen and Royal Cornfield Hospital, Aberdeen
A. J. Hedley
Affiliation:
University of Aberdeen and Royal Cornfield Hospital, Aberdeen
H. C. S. Maclean
Affiliation:
University of Aberdeen and Royal Cornfield Hospital, Aberdeen

Synopsis

A case of acute schizophrenic psychosis developing during the treatment of hyper-thyroidism with carbimazole is described. The patient was clinically and biochemically euthyroid at the time the psychosis developed. It is suggested that an acute alteration in thyroid status, without necessarily producing hyper- or hypothyroidism, may be sufficient to induce a psychotic reaction.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1971

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Asher, R. (1949). Myxoedematous madness. British Medical Journal, 2, 555562.CrossRefGoogle ScholarPubMed
Brewer, C. (1969). Psychosis due to acute hypothyroidism during the administration of carbimazole. British Journal of Psychiatry, 115, 11811183.CrossRefGoogle ScholarPubMed
Coppen, A. J. (1968). Depressed states and indolealkylamines. Advances in Pharmacology, 6B, 283291.CrossRefGoogle Scholar
Greer, S., and Parsons, V. (1968). Schizophrenia-like psychosis in thryoid crisis. British Journal of Psychiatry, 114, 13571362.CrossRefGoogle Scholar
SirGull, W. W. (1874). On a cretinoid state supervening in adult life in women. Transactions of the Clinical Society of London, 7, 180185.Google Scholar
Harrison, T. S. (1964). Adrenal medullary and thyroid relationships. Physiological Reviews, 44, 161185.CrossRefGoogle ScholarPubMed
Herridge, C. F., and Abey-Wickrama, I. (1969). Acute iatrogenic hypothyroid psychosis. British Medical Journal, 3, 154.CrossRefGoogle ScholarPubMed
Tóth, S., and Csaba, B. (1966). The effect of thyroid gland on 5-hydroxytryptamine (5-HT) level of brain stem and blood in rabbits. Experientia, 22, 755756.CrossRefGoogle Scholar
Williams, R. H., Clute, H. M., Anglem, T. J., and Kenney, F. R. (1946). Thiouracil treatment of thyrotoxicosis. II. Tonic reactions. Journal of Clinical Endocrinology, 6, 2351.CrossRefGoogle Scholar
Witton, K. (1958). Acute transitory psychotic reaction manifested after radioactive iodine treatment for hyper-thyroidism. American Journal of Psychiatry, 115, 746747.CrossRefGoogle Scholar