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Premenstrual depression, cortisol and oestradiol treatment

Published online by Cambridge University Press:  09 July 2009

J. L. Crammer
J. L. Crammer*
Affiliation:
Institute of Psychiatry, London
*
1Address for correspondence: Dr J. L. Crammer, Institute of Psychiatry, Dc Crespigny Park, Denmark Hill, London SE5 8AF.
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Synopsis

A woman with a 5-year history of frequently recurrent depressions responded poorly to the usual antidepressants. She had a raised plasma cortisol and was made worse by progesterone or by ACTH. An oestradiol/testosterone implant every 4 months abolished all symptoms for at least 8 years, and plasma cortisol returned to normal. This case is relevant to an understanding of premenstrual syndromes and the genesis of depressive illness.

Type
Case Report
Information
Psychological Medicine , Volume 16 , Issue 2 , May 1986 , pp. 451 - 455
Copyright
Copyright © Cambridge University Press 1986

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References

Cohen, S. I. (1980). Cushing's syndrome: a psychiatric study of 29 patients. British Journal of Psychiatry 136, 120–124.CrossRefGoogle ScholarPubMed
Cullberg, J. (1972). Mood change and menstrual symptoms with different gestagen/oestrogen combinations: a double-blind comparison with placebo. Acta Psychiatrica Scandinavica, Suppl. 236, 1–86. Munksgaard: Copenhagen.Google Scholar
Duffield, J. E. (1973). Side-effects of lithium carbonate. British Medical Journal i, 491.CrossRefGoogle Scholar
Labhart, A. (1974). Clinical Endocrinology: Theory and Practice (revised second edn). p. 353. Springer-Verlag: Berlin.CrossRefGoogle Scholar
Lachelin, G. C. L., Barnett, M., Hopper, B. R., Brink, G. & Yen, S. S. C. (1979). Adrenal function in normal women and women with the polycystic ovarian syndrome. Journal of Clinical Endocrinology 49, 892–898.CrossRefGoogle Scholar
Magos, A. L. & Studd, J. W. (1984). The premenstrual syndrome. In Progress in Obstetrics and Gynaecology, Vol. 4 (ed. Studd, J. W.), pp. 334–350. Churchill-Livingstone: Edinburgh.Google Scholar
Magos, A. L., Zilkha, K. J. & Studd, J. W. (1983). Treatment of menstrual migraine by oestradiol implants. Journal of Neurology, Neurosurgery and Psychiatry 46, 1044–1046.CrossRefGoogle ScholarPubMed
Munday, M. R., Brush, M. G. & Taylor, R. W. (1981). Correlations between progesterone, oestradiol and aldosterone levels in premenstrual syndrome. Clinical Endocrinology 14, 1–9.CrossRefGoogle ScholarPubMed
Muse, K. N., Cetel, N. S., Futterman, L. A. & Yen, S. S. C. (1984). The premenstrual syndrome: effects of ‘medical ovariectomy’. New England Journal of Medicine 311, 1345–1349.CrossRefGoogle ScholarPubMed
Rubinow, D. R. & Roy-Byrne, P. (1984). Premenstrual syndromes: overview from a methodologic perspective. American Journal of Psychiatry 141, 163–172.Google ScholarPubMed
Watts, J. F., Butt, W. R., Logan-Edwards, R. & Holder, G. (1985). Hormonal studies in women with premenstrual tension. British Journal of Obstetrics and Gynaecology 92, 247–255.CrossRefGoogle ScholarPubMed