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Preliminary Communication Thyro-endocrine pathology, obstetric morbidity and schizophrenia: survey of a hundred families with a schizophrenic proband

Published online by Cambridge University Press:  09 July 2009

David MacSweeney ,
Pauline Timms  and
Anthony Johnson
David MacSweeney*
Affiliation:
MRC Neuropsychiatry Unit, Carshalton and West Park Hospital, Epsom, Surrey
Pauline Timms
Affiliation:
MRC Neuropsychiatry Unit, Carshalton and West Park Hospital, Epsom, Surrey
Anthony Johnson
Affiliation:
MRC Neuropsychiatry Unit, Carshalton and West Park Hospital, Epsom, Surrey
*
1Address for correspondence: Dr David MacSweeney, Academic Department of Psychiatry, Middlesex Hospital Medical School, London W1P 8AA.
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Synopsis

This preliminary communication reports that the mothers of 104 schizophrenic patients had: (1) a significantly higher incidence of thyroid disease than a carefully matched control group; (2) significantly more abortions, still-births and greater infant mortality. The findings and possible relevance of thyroid disease to schizophrenia are discussed. Three prospective studies currently in progress are outlined.

Type
Research Article
Information
Psychological Medicine , Volume 8 , Issue 1 , February 1978 , pp. 151 - 155
Copyright
Copyright © Cambridge University Press 1978

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