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Preliminary Communication Absence of cardiac deceleration in a signalled escape paradigm: a psychophysiological deficit in chronic schizophrenia

Published online by Cambridge University Press:  09 July 2009

John L. Waddington ,
Malcolm J. Macculloch ,
Marie L. Schalken  and
Jean E. Sambrooks
John L. Waddington*
Affiliation:
Department of Psychiatry, University of Liverpool
Malcolm J. Macculloch
Affiliation:
Department of Psychiatry, University of Liverpool
Marie L. Schalken
Affiliation:
Department of Psychiatry, University of Liverpool
Jean E. Sambrooks
Affiliation:
Department of Psychiatry, University of Liverpool
*
1Address for correspondence: Dr J. L. Waddington, Division of Psychiatry, MRC Clinical Research Centre, Harrow, Middlesex HA1 3UJ.
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Synopsis

Fourteen chronic male schizophrenic patients and six male control subjects were com pared in an escape paradigm involving temporal warning of the presentation of an aversive tone stimulus to which an escape response was to be made. The characteristic heart rate deceleration shown immediately prior to the aversive stimulus by control subjects was absent in the schizophrenic group. Further features of this novel test paradigm distinguished the control and schizophrenic groups. This psychophysiological test procedure may be fruitful for schizophrenia research.

Type
Research Article
Information
Psychological Medicine , Volume 8 , Issue 1 , February 1978 , pp. 157 - 162
Copyright
Copyright © Cambridge University Press 1978

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References

Elliott, R. (1972). The significance of heart rate for behaviour: A critique of Lacey's hypothesis. Journal of Personality and Social Psychology 22, 398–409.Google Scholar
Flekkoy, K. (1975). Psychophysiological and neurophysiological aspects of schizophrenia. Acta Psychiatrica Scandinavica 51, 234–248.Google Scholar
Ganong, W. F. (1969). Review of Medical Physiology. Lange: Los Altos.Google Scholar
Gruzelier, J. H. & Hammond, N. V. (1974). The effect of chlorpromazine upon the psychophysiology of chronic schizophrenics. Paper presented to the Second Scientific meeting of the Psychophysiology Group, British Psychological Society, London.Google Scholar
Hahn, W. W. (1973). Attention and heart rate: A critical appraisal of the hypothesis of Lacey and Lacey. Psychological Bulletin 79, 59–70.CrossRefGoogle ScholarPubMed
Klawans, H. L. (1973). Pharmacology of tardive dyskinesias. American Journal of Psychiatry 130, 82–86.Google Scholar
Lacey, J. I. (1967). Somatic response patterning and stress: Some revisions of activation theory. In Psychological Stress (ed. Appley, M. H. and Trumball, R.), pp. 14–42. Appleton: New York.Google Scholar
Lacey, J. I. & Lacey, B. C. (1970). Some autonomic-central nervous system inter-relationships. In Physiological Correlates of Emotion (ed. Black, P.), pp. 205–207. Academic Press: New York.Google Scholar
Lacey, J. I. & Lacey, B. C. (1974). On heart rate responses and behaviour. A reply to Elliott. Journal of Personality and Social Psychology 30, 1–18.CrossRefGoogle ScholarPubMed
Lang, P.J. & Buss, A. H. (1965). Psychological deficit in schizophrenia. II. Interference and activation. Journal of Abnormal Psychology 70, 77–106.Google Scholar
Obrist, P. A. (1975). The cardiovascular-behavioural interaction – as it appears today. Psychophysiology 13, 95–107.CrossRefGoogle Scholar
Obrist, P. A., Black, A. H., Brener, J. & DiCara, L. (1974). Cardiovascular Psychophysiology-Current Issues in Re sponse Mechanisms, Biofeedback and Methodology. Aldine: Chicago.Google Scholar
Sandman, C. A., McCanne, T. R., Kaiser, D. N. & Diamond, B. (1977). Heart rate and cardiac phase influences on visual perception. Journal of Comparative and Physiological Psychology 91, 189–202.Google Scholar
Spohn, H. E., Thetford, P. E. & Cancro, P. (1971). The effects of phenothiazine medication on skin conductance and heart rate in schizophrenic patients. Journal of Nervous and Mental Disease 152, 129–139.CrossRefGoogle ScholarPubMed
Tecce, J. J. & Cole, J. C. (1972). Psychophysiologic responses of schizophrenics to drugs. Psychopharmacologia 24, 159–200.CrossRefGoogle ScholarPubMed
Venables, P. H. (1975). Psychophysiological studies of schizophrenic pathology. In Research in Psychophysiology (ed. Venables, P. H. and Christie, M. J.), pp. 282–324. Wiley: London.Google Scholar
Wilson, R. S. (1974). Cardivar: The statistical analysis of heart rate data. Psychophysiology 11, 76–85.Google Scholar